An investigation of the polar extracts from a starfish, collected in the Antarctic Sea, and identified as belonging to the Echinasteridae family, has led to the isolation of seven sulphated asterosaponins. Five are new compounds. The isolated asterosaponins have been found to be cytotoxic against human bronchopulmunary non-small-cell-lung carcinoma cells at IC50 < 3.3 mu g/ml.
Starfish Saponins: part 54. Cytotoxic asterosaponins from an Antarctic starfish of the family Echinasteridae / DE MARINO, Simona; L., Minale; Zollo, Franco; M., Iorizzi; V., Le Bert; C., Roussakis. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - STAMPA. - 126:(1996), pp. 667-672.
Starfish Saponins: part 54. Cytotoxic asterosaponins from an Antarctic starfish of the family Echinasteridae
DE MARINO, SIMONA;ZOLLO, FRANCO;
1996
Abstract
An investigation of the polar extracts from a starfish, collected in the Antarctic Sea, and identified as belonging to the Echinasteridae family, has led to the isolation of seven sulphated asterosaponins. Five are new compounds. The isolated asterosaponins have been found to be cytotoxic against human bronchopulmunary non-small-cell-lung carcinoma cells at IC50 < 3.3 mu g/ml.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
