We compared the intergenerational variations of the clinical phenotype between 30 patients affected with multiple autoimmune syndrome (MAS) and their affected first- and second-degree relatives. Mean age at onset was always significantly higher in the previous generation than in probands for all the considered diseases. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
Intergenerational anticipation of disease onset in people with multiple autoimmune syndrome / Giardino, G.; Aloj, Giuseppina; Cirillo, Emilia; Capalbo, Donatella; Maio, F.; Salerno, Mariacarolina; Franzese, Adriana; Pignata, Claudio. - In: DIABETES RESEARCH AND CLINICAL PRACTICE. - ISSN 0168-8227. - 94:2(2011), pp. e37-e39. [10.1016/j.diabres.2011.07.022]
Intergenerational anticipation of disease onset in people with multiple autoimmune syndrome.
Giardino G.;ALOJ, GIUSEPPINA;CIRILLO, EMILIA;CAPALBO, DONATELLA;SALERNO, MARIACAROLINA;FRANZESE, ADRIANA;PIGNATA, CLAUDIO
2011
Abstract
We compared the intergenerational variations of the clinical phenotype between 30 patients affected with multiple autoimmune syndrome (MAS) and their affected first- and second-degree relatives. Mean age at onset was always significantly higher in the previous generation than in probands for all the considered diseases. (C) 2011 Elsevier Ireland Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
