Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge N. superstes collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as by comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells.
Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonian spongeNeosiphonia superstes / D'Auria, MARIA VALERIA; Gomez Paloma, L.; Minale, L.; Zampella, Angela; Verbist, J. F.; Roussakis, C.; Debitus, C.. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 49:38(1993), pp. 8645-8657. [10.1016/S0040-4020(01)96271-4]
Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonian spongeNeosiphonia superstes
D'AURIA, MARIA VALERIA;ZAMPELLA, ANGELA;
1993
Abstract
Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge N. superstes collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as by comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
