Rat peritoneal luecocytes incubated with hydrocortisone (10 micrograms/ml) release a factor which inhibits prostaglandin generation. The steroid-induced inhibitor, which mediates the anti-phospholipase effect of antiinflammatory steroids, may be a protein or a polypeptide since its formation is blocked by cycloheximide, a known inhibitor of protein synthesis.
Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes / Carnuccio, Rosa; M. D., Rosa; P., Persico. - In: BRITISH JOURNAL OF PHARMACOLOGY. - ISSN 0007-1188. - STAMPA. - 68:(1980), pp. 14-16.
Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes.
CARNUCCIO, ROSA;
1980
Abstract
Rat peritoneal luecocytes incubated with hydrocortisone (10 micrograms/ml) release a factor which inhibits prostaglandin generation. The steroid-induced inhibitor, which mediates the anti-phospholipase effect of antiinflammatory steroids, may be a protein or a polypeptide since its formation is blocked by cycloheximide, a known inhibitor of protein synthesis.File in questo prodotto:
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