A new organocatalyst, synthesized from D-glucosamine and L-proline, is capable of acting like an enzyme in the accomplishment of direct aldol reactions. Excellent results, in terms of chemical yields, as well as diastereomeric and enantiomeric ratios, are reported for the catalyzed additions of cyclohexanone and acetone to variously substituted benzaldehydes.
D-Glucosamine in a chimeric prolinamide organocatalyst for direct asymmetric aldol addition / DE NISCO, Mauro; Pedatella, Silvana; S., Bektaş; A., Nucci; Caputo, Romualdo. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - 356:(2012), pp. 273-277. [10.1016/j.carres.2012.03.041]
D-Glucosamine in a chimeric prolinamide organocatalyst for direct asymmetric aldol addition.
DE NISCO, MAURO;PEDATELLA, SILVANA;CAPUTO, ROMUALDO
2012
Abstract
A new organocatalyst, synthesized from D-glucosamine and L-proline, is capable of acting like an enzyme in the accomplishment of direct aldol reactions. Excellent results, in terms of chemical yields, as well as diastereomeric and enantiomeric ratios, are reported for the catalyzed additions of cyclohexanone and acetone to variously substituted benzaldehydes.| File | Dimensione | Formato | |
|---|---|---|---|
|
Pedatella_2012_CarbRes.rar
accesso aperto
Tipologia:
Documento in Post-print
Licenza:
Accesso privato/ristretto
Dimensione
212.33 kB
Formato
Unknown
|
212.33 kB | Unknown | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
