Valuation of hematic and parenchymal levels of flunoxaprofen and of hepato-renal and hematopoietic functionality in horses treated by therapeutical dosages

Six horses, both males and females between 7 and 10 years old, have been treated for 10 days by 1.5 mg/kg of Flunoxaprofen taken orally. Notwithstanding the accumulation of the drug in the analyzed parenchyma, the resyults of researchers made during and at the end of the treatment do not show any modifications in homeometric values nor in hematochemical constants, both considered as expressions of the functionality of the liver and kidney. A progressive increase of Flunoxaprofen plasma levels in treated horses has been observed, as the administration is progressing. The Authors because of Flunoxaprofen cumulation, think better a reduction of dosage in long-term/therapy of subjects suffering with hepato-renal disease.