Me 6-O-trityl-α-D-glucopyranoside or its partially acetylated derivs. were refluxed in C6H6 in the presence of anhyd. CuSO4 to give 85-100% corresponding detritylated compds. without hydrolysis or migration of other groups. Of the bivalent-metallic (Cu2+, Ni2+, Fe2+, Co2+, and Zn2+) sulfate catalysts used, CuSO4 gave the best results. C6H6 was the solvent of choice; toluene and xylene caused partial isomerization and in some cases hydrolysis of the Ac groups
A simple method for detritylation of carbohydrate derivatives / Randazzo, G.; Capasso, R.; Cicala, M. R.; Evidente, Antonio. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - STAMPA. - 85:(1980), pp. 298-301.
A simple method for detritylation of carbohydrate derivatives
EVIDENTE, ANTONIO
1980
Abstract
Me 6-O-trityl-α-D-glucopyranoside or its partially acetylated derivs. were refluxed in C6H6 in the presence of anhyd. CuSO4 to give 85-100% corresponding detritylated compds. without hydrolysis or migration of other groups. Of the bivalent-metallic (Cu2+, Ni2+, Fe2+, Co2+, and Zn2+) sulfate catalysts used, CuSO4 gave the best results. C6H6 was the solvent of choice; toluene and xylene caused partial isomerization and in some cases hydrolysis of the Ac groupsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
