Two different populations of the marine sponges Cliona copiosa, collected in two different sites of the Mediterranean sea, were examined for polyoxygenated sterols. C. copiosa from the bay of Naples contained 5-alpha-cholestane-3-beta,5, 6-beta-triol [1] and the new trihydroxysterols (22E)-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [2], (22E,24S)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [3], (22E,24R)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [4], (24R)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [5], and (24S)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [6]. The population collected from Marsala lagoon, Sicily, contained only sterols 1, 5, and 6. The structures of these compounds were deduced by analysis of spectral data. Partial synthesis of compounds 1, 5, and 6 confirmed the structure assignment
3-BETA,5-ALPHA,6-BETA-TRIHYDROXYLATED STEROLS WITH A SATURATED NUCLEUS FROM 2 POPULATIONS OF THE MARINE SPONGE CLIONA-COPIOSA / Notaro, G.; Piccialli, Vincenzo; Sica, D.; Corriero, G.. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - STAMPA. - 54:6(1991), pp. 1570-1575. [10.1021/np50078a012]
3-BETA,5-ALPHA,6-BETA-TRIHYDROXYLATED STEROLS WITH A SATURATED NUCLEUS FROM 2 POPULATIONS OF THE MARINE SPONGE CLIONA-COPIOSA
PICCIALLI, VINCENZO;
1991
Abstract
Two different populations of the marine sponges Cliona copiosa, collected in two different sites of the Mediterranean sea, were examined for polyoxygenated sterols. C. copiosa from the bay of Naples contained 5-alpha-cholestane-3-beta,5, 6-beta-triol [1] and the new trihydroxysterols (22E)-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [2], (22E,24S)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [3], (22E,24R)-24-methyl-5-alpha-cholest-22-ene-3-beta,5,6-beta-triol [4], (24R)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [5], and (24S)-24-ethyl-5-alpha-cholestane-3-beta,5,6-beta-triol [6]. The population collected from Marsala lagoon, Sicily, contained only sterols 1, 5, and 6. The structures of these compounds were deduced by analysis of spectral data. Partial synthesis of compounds 1, 5, and 6 confirmed the structure assignmentI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
