Two new representatives of the rare class of bisnorditerpenes, gracilin C (I) and D II were isolated as minor metabolites from S. gracilis, a Mediterranean sponge. The structure of these compds., both related to that of gracilin B (III), the major metabolite of S. gracilis, were solved by spectral analyses, including 2-dimensional NMR spectroscopy, and chem. interconversions. The structure of III was revised on the basis of addnl. NOE difference expts. and 13C NMR data.
MINOR BISNORDITERPENES FROM THE MARINE SPONGE SPONGIONELLA-GRACILIS AND REVISION OF THE DELTA-6 CONFIGURATION OF GRACILIN-B / Mayol, Luciano; Piccialli, Vincenzo; Sica, D.. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - STAMPA. - 49:5(1986), pp. 823-828. [10.1021/np50047a010]
MINOR BISNORDITERPENES FROM THE MARINE SPONGE SPONGIONELLA-GRACILIS AND REVISION OF THE DELTA-6 CONFIGURATION OF GRACILIN-B
MAYOL, LUCIANO;PICCIALLI, VINCENZO;
1986
Abstract
Two new representatives of the rare class of bisnorditerpenes, gracilin C (I) and D II were isolated as minor metabolites from S. gracilis, a Mediterranean sponge. The structure of these compds., both related to that of gracilin B (III), the major metabolite of S. gracilis, were solved by spectral analyses, including 2-dimensional NMR spectroscopy, and chem. interconversions. The structure of III was revised on the basis of addnl. NOE difference expts. and 13C NMR data.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
