β-homoDNA has the singular property of being able to pair with homochiral complements of opposite chirality, with a greater stability than that observed in the corresponding isochiral complexes. Relevant to etiological investigations on nucleic acid structure, these results suggest the existence of a relationship between carbohydrate structure and stereoselectivity of the hybridization processes of the corresponding nucleic acids.
Enantiomeric Selection Properties of beta-homoDNA: Enhanced Pairing for Heterochiral Complexes / D'Alonzo, Daniele; Amato, Jussara; Guy, Schepers; Matheus, Froeyen; Arthur Van, Aerschot; Piet, Herdewijn; Guaragna, Annalisa. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - 52:26(2013), pp. 6662-6665. [10.1002/anie.201301659]
Enantiomeric Selection Properties of beta-homoDNA: Enhanced Pairing for Heterochiral Complexes
D'ALONZO, DANIELE;AMATO, JUSSARA;GUARAGNA, ANNALISA
2013
Abstract
β-homoDNA has the singular property of being able to pair with homochiral complements of opposite chirality, with a greater stability than that observed in the corresponding isochiral complexes. Relevant to etiological investigations on nucleic acid structure, these results suggest the existence of a relationship between carbohydrate structure and stereoselectivity of the hybridization processes of the corresponding nucleic acids.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
