Why nature selected 5,6-dihydroxyindole-2-carboxylic acid (DHICA) to synthesize (photo)protective eumelanin pigments is an enigma. Synthetic DHICA eumelanin has now been shown to be a highly efficient free-radical scavenger in the solid state, which is due to a conformationally interrupted π-electron network associated with atypical optical, paramagnetic, and aggregation properties.
Atypical Structural and pi-Electron Features of a Melanin Polymer That Lead to Superior Free-Radical-Scavenging Properties / Panzella, Lucia; Gentile, G.; D'Errico, Gerardino; Della Vecchia, Nicola Fyodor; Errico, M. E.; Napolitano, Alessandra; Carfagna, Cosimo; D'Ischia, Marco. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - 52:48(2013), pp. 12684-12687. [10.1002/anie.201305747]
Atypical Structural and pi-Electron Features of a Melanin Polymer That Lead to Superior Free-Radical-Scavenging Properties
PANZELLA, LUCIA;D'ERRICO, GERARDINO;Della Vecchia, Nicola Fyodor;NAPOLITANO, ALESSANDRA;CARFAGNA, COSIMO;D'ISCHIA, MARCO
2013
Abstract
Why nature selected 5,6-dihydroxyindole-2-carboxylic acid (DHICA) to synthesize (photo)protective eumelanin pigments is an enigma. Synthetic DHICA eumelanin has now been shown to be a highly efficient free-radical scavenger in the solid state, which is due to a conformationally interrupted π-electron network associated with atypical optical, paramagnetic, and aggregation properties.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
