The condroprotector role in the osteoarthritis of the KNEE

This work is a clinical study designed with the aim to assess the effects of a packet containing 500 mg of glucosamine sulfate, 400mg of chondroitin sulfate, 100mg of Vitamin C, 2 mg of manganese, 100 mg of curcumina in some patients affected by primary osteoarthritis (OA). Our research was conducted during eighteen months from 2010 to 2011 in some patients affected by primary osteoarthritis of the knee. The study evaluated 300 patients. 150 patients were enrolled and divided into three subgroups. Most patients enrolled were female (60%), with a mean age of 54 years old and weight about 70kg. We assessed the pain, the joint functions adverse events, the joint noise. We measured the pain according to the VAS scale (from 0 to 10). The VAS score reduction was statistically significant after 12 weeks. The pain related to the joint load, also measured according to the VAS score, showed a significant reduction during the fourth week. Improvements in the rigidity and in some difficulties related to the normal physical activities were observed during the ninth week. It was really important the arrangement of the elements constituting the integrator, because they are responsible for the evident improvement of daily physical activities.