Superficial chemical peeling with a lipophilic derivative salicylic acid in chrono and photoaging

Chronoaging, photoaging and mechanical stress induce profound alterations of skin structure. The intrinsic aging also known as chronological aging is due to genetic factors and metabolic processes, including hormonal alteration that induce dermal and hypodermal atrophy in elderly. Extrinsic aging or environmental aging is prevalently promoted by sun exposure. Therefore the improvement of fine lines, wrinkles and hyperpigmentation marks is one of the most important field of interest of dermocosmetology. Since several years chemical peelings are used to improve the appearance of damaged skin, in this study was evaluated the effectiveness of a salicylic acid derivative known as β-lipohydroxy acid (LHA™, BIOMEDIC LHA-PEEL®) on the face of marked signs of aging. Were enrolled 20 volunteers women aged between 45 and 65 years; 5% LHATM was applied once weekly for two weeks and 10% LHATM was used once every 14 days for three steps. To evalue the efficacy of the peeling were carry out clinical examination, photographic study and cutaneous non invasive evaluations, such as colorimetry (Spectrocolorimeter X-Rite®) and corneometry (Corneometer CM 820®). The results have showed a significant increase of skin hydration middle and an improvement in complexion clearness. The volunteers experienced cosmetic benefits in the clinical parameters like reported by a self-evaluation questionnaire. Therefore, the lipophilic derivative salicylic acid has showed an elevated tolerance without minimal adverse erythematous events