A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (alpha, beta, Me beta CD and HP beta CD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.
A novel synthetic strategy for mono-substituted cyclodextrin derivatives / DI FABIO, Giovanni; Malgieri, G.; Isernia, C.; D'Onofrio, Jennifer; Gaglione, M.; Messere, A.; Zarrelli, Armando; DE NAPOLI, Lorenzo. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 48:32(2012), pp. 3875-3877. [10.1039/c2cc30550j]
A novel synthetic strategy for mono-substituted cyclodextrin derivatives
DI FABIO, GIOVANNI;D'ONOFRIO, JENNIFER;ZARRELLI, ARMANDO;DE NAPOLI, LORENZO
2012
Abstract
A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (alpha, beta, Me beta CD and HP beta CD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
