A group of 88 patients affected with vitiligo were treated by epidermoabrasion and daily applications of 5-fluorouracil (5-FU) or cyclosporin A (CyA) with occlusive dressing for 15 days. Repigmentation was observed in 70% patients treated with 5-FU and in 5,5% of patients treated with CyA. Repigmentation appeared 4-8 weeks after suspension of treatment and was complete after 5-6 months. No side effects were observed. The action of the two drugs is discussed.
VITILIGINE A PICCOLE CHIAZZE: ABRASIONE EPIDERMICA E 5-FU VERSUS ABRASIONE EPIDERMICA E CYA / Procaccini, Em; Delfino, Mario; Monfrecola, Giuseppe. - In: DERMATOLOGIA OGGI. - ISSN 0394-2503. - 6:2(1991), pp. 24-27.
VITILIGINE A PICCOLE CHIAZZE: ABRASIONE EPIDERMICA E 5-FU VERSUS ABRASIONE EPIDERMICA E CYA
DELFINO, MARIO;MONFRECOLA, GIUSEPPE
1991
Abstract
A group of 88 patients affected with vitiligo were treated by epidermoabrasion and daily applications of 5-fluorouracil (5-FU) or cyclosporin A (CyA) with occlusive dressing for 15 days. Repigmentation was observed in 70% patients treated with 5-FU and in 5,5% of patients treated with CyA. Repigmentation appeared 4-8 weeks after suspension of treatment and was complete after 5-6 months. No side effects were observed. The action of the two drugs is discussed.| File | Dimensione | Formato | |
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