Bartonella henselae is the etiologic agent of cat-scratch disease. B. henselae infections are responsible for a widening spectrum of human diseases, although often symptomless, ranging from self-limited to life-threatening and show different courses and organ involvement due to the balance between host and pathogen. The role of the host immune response to B. henselae is critical in preventing progression to systemic disease. Indeed in immunocompromised patients, such as solid organ transplant patients, B. henselae results in severe disseminated disease and pathologic vasoproliferation. The purpose of this study was to determine the seroprevalence of B. henselae in patients awaiting heart transplant compared to healthy individuals enrolled in the Regional Reference Laboratory of Transplant Immunology of Second University of Naples.
Seroprevalence of Bartonella henselae in patients awaiting heart transplant in Southern Italy / Picascia, A; Pagliuca, Chiara; Sommese, L; Colicchio, Roberta; Casamassimi, A; Labonia, Francesco; Pastore, G; Pagliarulo, C; Cicatiello, ANNUNZIATA GAETANA; Castaldo, F; Schiano, C; Maiello, C; Mezza, Ernesto; D'Armiento, FRANCESCO PAOLO; Salvatore, Paola; Napoli, C.. - In: WEI-MIAN YU GANRAN ZAZHI. - ISSN 1684-1182. - 50:2(2017), pp. 239-244. [10.1016/j.jmii.2015.05.001]
Seroprevalence of Bartonella henselae in patients awaiting heart transplant in Southern Italy
PAGLIUCA, CHIARA;COLICCHIO, ROBERTA;LABONIA, FRANCESCO;CICATIELLO, ANNUNZIATA GAETANA;MEZZA, ERNESTO;D'ARMIENTO, FRANCESCO PAOLO;SALVATORE, PAOLA;
2017
Abstract
Bartonella henselae is the etiologic agent of cat-scratch disease. B. henselae infections are responsible for a widening spectrum of human diseases, although often symptomless, ranging from self-limited to life-threatening and show different courses and organ involvement due to the balance between host and pathogen. The role of the host immune response to B. henselae is critical in preventing progression to systemic disease. Indeed in immunocompromised patients, such as solid organ transplant patients, B. henselae results in severe disseminated disease and pathologic vasoproliferation. The purpose of this study was to determine the seroprevalence of B. henselae in patients awaiting heart transplant compared to healthy individuals enrolled in the Regional Reference Laboratory of Transplant Immunology of Second University of Naples.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.