Spine motility analysis has become the mainstay for investigating synaptic plasticity but is limited in its versatility requiring complex, non automatized instrumentations. We describe an entropy-based method for determining the spatial distribution of dendritic spines that allows successful estimation of spine motility from still images. This method has the potential to extend the applicability of spine motility analysis to ex vivo preparations.
Quantifying barcodes of dendritic spines using entropy-based metrics / Viggiano, Davide; Srivastava, D. P; Speranza, Luisa; PERRONE CAPANO, Carla; Bellenchi, G. C; di Porzio, U; Buckley, N. J.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 5:(2015), p. 14622. [10.1038/srep14622]
Quantifying barcodes of dendritic spines using entropy-based metrics
VIGGIANO, DAVIDE;SPERANZA, LUISA;PERRONE CAPANO, CARLA;
2015
Abstract
Spine motility analysis has become the mainstay for investigating synaptic plasticity but is limited in its versatility requiring complex, non automatized instrumentations. We describe an entropy-based method for determining the spatial distribution of dendritic spines that allows successful estimation of spine motility from still images. This method has the potential to extend the applicability of spine motility analysis to ex vivo preparations.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
