CHARGE association is characterized by ocular Coloboma, Heart malformations, choanal Atresia, Retardation of growth and development, Genital abnormalities and inner and external Ear abnormalities. Growth failure is a frequent find mainly associated with feeding difficulties or systemic diseases. To date, GH deficiency has been reported in only few patients with CHARGE association however long-term effects of GH treatment, up to final height, have never been reported. We describe a patient with CHARGE association and GH deficiency treated with GH from the age of 3 years and 10 months up to adult height.
Effect of long-term GH treatment in a patient with CHARGE association / Esposito, A; Tufano, M; Di Donato, I; Rezzuto, M; Improda, Nicola; Melis, Daniela; Salerno, Mariacarolina. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1824-7288. - 40:1(2014), p. 51. [10.1186/1824-7288-40-51]
Effect of long-term GH treatment in a patient with CHARGE association
IMPRODA, NICOLA;MELIS, DANIELA;SALERNO, MARIACAROLINA
2014
Abstract
CHARGE association is characterized by ocular Coloboma, Heart malformations, choanal Atresia, Retardation of growth and development, Genital abnormalities and inner and external Ear abnormalities. Growth failure is a frequent find mainly associated with feeding difficulties or systemic diseases. To date, GH deficiency has been reported in only few patients with CHARGE association however long-term effects of GH treatment, up to final height, have never been reported. We describe a patient with CHARGE association and GH deficiency treated with GH from the age of 3 years and 10 months up to adult height.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
