Omega (ω)-3 polyunsaturated fatty acids (PUFA) are dietary compounds able to attenuate insulin resistance. Anyway, the precise actions of ω-3PUFAs in skeletal muscle are overlooked. We hypothesized that PUFAs, modulating mitochondrial function and efficiency, would ameliorate pro-inflammatory and pro-oxidant signs of nutritionally induced obesity.
Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle / Cavaliere, Gina; Trinchese, Giovanna; Bergamo, Paolo; DE FILIPPO, Chiara; MATTACE RASO, Giuseppina; Gifuni, Giorgio; Putti, Rosalba; Moni, Bottu Heleena; BERNI CANANI, Roberto; Meli, Rosaria; Mollica, MARIA PINA. - In: PLOS ONE. - ISSN 1932-6203. - 11:2(2016), pp. 149033-149051. [10.1371/journal.pone.0149033]
Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle
CAVALIERE, Gina;TRINCHESE, GIOVANNA;BERGAMO, PAOLO;DE FILIPPO, Chiara;MATTACE RASO, GIUSEPPINA;GIFUNI, GIORGIO;PUTTI, ROSALBA;BERNI CANANI, ROBERTO;MELI, ROSARIA;MOLLICA, MARIA PINA
2016
Abstract
Omega (ω)-3 polyunsaturated fatty acids (PUFA) are dietary compounds able to attenuate insulin resistance. Anyway, the precise actions of ω-3PUFAs in skeletal muscle are overlooked. We hypothesized that PUFAs, modulating mitochondrial function and efficiency, would ameliorate pro-inflammatory and pro-oxidant signs of nutritionally induced obesity.| File | Dimensione | Formato | |
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