In the field of Industrial Hygiene, airborne particulate matter is traditionally defined as small particles made up of solid substances, little drops of liquid or microbiologic organisms. There is a strict correlation between the size of particles and their potentially harmful effects on health. Fine particles, i.e. less than 2.5 micrometers in diameter, have been particularly associated with premature mortality and other serious health effects. Animal studies on mice exposed to fine particles from an early age, have shown of secretory changes in the nasal cavity, with increased production of acidic muco-substances. In the course of further studies that are needed to define the effects of PM 2.5 particles on the nasal mucosa of humans, olfactometry could be used as a screening test to find first initial alterations caused by fine particles.
Effetti del particolato aerodisperso fine sulla mucosa nasale / Passali, G. C.; Iavicoli, Ivo; Magrini, A.; Calò, L.; Rigante, M.; Paludetti, G.; Bergamaschi, A.. - In: GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA. - ISSN 1592-7830. - 28:3 SUPPL.(2006), pp. 40-42.
Effetti del particolato aerodisperso fine sulla mucosa nasale
IAVICOLI, Ivo;
2006
Abstract
In the field of Industrial Hygiene, airborne particulate matter is traditionally defined as small particles made up of solid substances, little drops of liquid or microbiologic organisms. There is a strict correlation between the size of particles and their potentially harmful effects on health. Fine particles, i.e. less than 2.5 micrometers in diameter, have been particularly associated with premature mortality and other serious health effects. Animal studies on mice exposed to fine particles from an early age, have shown of secretory changes in the nasal cavity, with increased production of acidic muco-substances. In the course of further studies that are needed to define the effects of PM 2.5 particles on the nasal mucosa of humans, olfactometry could be used as a screening test to find first initial alterations caused by fine particles.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
