The guidelines of the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition allow for diagnosis of celiac disease without biopsies in children with symptoms and levels of immunoglobulin A against tissue-transglutaminase (TGA-IgA) 10-fold or more the upper limit of normal (ULN), confirmed by detection of endomysium antibodies (EMA) and positivity for HLA-DQ2/DQ8. We performed a large, international prospective study to validate this approach.

Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice / Werkstetter, K.J., Korponay Szabó, I.R., Popp, A., Villanacci, V., Salemme, M., Heilig, G., Lillevang, S.T., Mearin, M.L., Ribes Koninckx, C., Thomas, A., Troncone, R., Filipiak, B., Mäki, M., Gyimesi, J., Najafi, M., Dolinšek, J., Dydensborg Sander, S., Auricchio, R., Papadopoulou, A., Vécsei, A., et al.. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - (2017). [10.1053/j.gastro.2017.06.002]

Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice

TRONCONE, RICCARDO;AURICCHIO, RENATA;KOSOVA, ROBERTA;MAGLIO, MARIANTONIA;
2017

Abstract

The guidelines of the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition allow for diagnosis of celiac disease without biopsies in children with symptoms and levels of immunoglobulin A against tissue-transglutaminase (TGA-IgA) 10-fold or more the upper limit of normal (ULN), confirmed by detection of endomysium antibodies (EMA) and positivity for HLA-DQ2/DQ8. We performed a large, international prospective study to validate this approach.
2017
Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice / Werkstetter, K.J., Korponay Szabó, I.R., Popp, A., Villanacci, V., Salemme, M., Heilig, G., Lillevang, S.T., Mearin, M.L., Ribes Koninckx, C., Thomas, A., Troncone, R., Filipiak, B., Mäki, M., Gyimesi, J., Najafi, M., Dolinšek, J., Dydensborg Sander, S., Auricchio, R., Papadopoulou, A., Vécsei, A., et al.. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - (2017). [10.1053/j.gastro.2017.06.002]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/681251
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