Interferon gamma (IFNG) is a pro-inflammatory cytokine produced mostly by T-lymphocytes during immune response to bacterial infections like bovine tuberculosis (bTB). Outcome of bTB infection is influenced by host genetic background, and impaired IFNG expression is often associated with poor prognosis for tuberculosis infection. Thus, in this study we evaluated the effects of IFNG polymorphisms on resistance/susceptibility to bTB in Mediterranean water buffalo (Bubalus bubalis).
The SNP g.4667G>A at 3’UTR of IFNG gene is associated with susceptibility to bovine tuberculosis in Mediterranean water buffalo (Bubalus bubalis) / Iannaccone, M.; Cosenza, G.; Pauciullo, A.; Martino, G.; Capparelli, R.. - In: ANIMAL GENETICS. - ISSN 1365-2052. - 49:5(2018), pp. 496-497. [10.1111/age.12698]
The SNP g.4667G>A at 3’UTR of IFNG gene is associated with susceptibility to bovine tuberculosis in Mediterranean water buffalo (Bubalus bubalis)
IANNACCONE M.
;COSENZA G.
;CAPPARELLI R.Membro del Collaboration Group
2018
Abstract
Interferon gamma (IFNG) is a pro-inflammatory cytokine produced mostly by T-lymphocytes during immune response to bacterial infections like bovine tuberculosis (bTB). Outcome of bTB infection is influenced by host genetic background, and impaired IFNG expression is often associated with poor prognosis for tuberculosis infection. Thus, in this study we evaluated the effects of IFNG polymorphisms on resistance/susceptibility to bTB in Mediterranean water buffalo (Bubalus bubalis).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
