After its discovery as a key controller of metabolic function, leptin has been later extensively implicated in additional functions including important modulatory activities on the innate and adaptive immune response. This review analyzes the known implications of leptin in multiple inflammatory conditions, including autoimmune diseases, and how this knowledge could be instrumental in the design of leptin-based manipulation strategies to help restoration of abnormal immune responses.
Leptin in inflammation and autoimmunity / La Cava, Antonio. - In: CYTOKINE. - ISSN 1043-4666. - 98:(2017), pp. 51-58. [10.1016/j.cyto.2016.10.011]
Leptin in inflammation and autoimmunity
La Cava, Antonio
2017
Abstract
After its discovery as a key controller of metabolic function, leptin has been later extensively implicated in additional functions including important modulatory activities on the innate and adaptive immune response. This review analyzes the known implications of leptin in multiple inflammatory conditions, including autoimmune diseases, and how this knowledge could be instrumental in the design of leptin-based manipulation strategies to help restoration of abnormal immune responses.File in questo prodotto:
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