Vagiallene (1), a rearranged C15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra.
Vagiallene, a Rearranged C15 Acetogenin from Laurencia obtusa / Perdikaris, Stamatios; Mangoni, Alfonso; Grauso, Laura; Papazafiri, Panagiota; Roussis, Vassilios; Ioannou, Efstathia. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 21:9(2019), pp. 3183-3186. [10.1021/acs.orglett.9b00897]
Vagiallene, a Rearranged C15 Acetogenin from Laurencia obtusa
Mangoni, AlfonsoSecondo
;Grauso, Laura;
2019
Abstract
Vagiallene (1), a rearranged C15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
