The medicinal gold(III) dithiocarbamato complex AuL12 forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.

Structural Characterization of a Gold/Serum Albumin Complex / Pratesi, Alessandro; Cirri, Damiano; Fregona, Dolores; Ferraro, Giarita; Giorgio, Anna; Merlino, Antonello; Messori, Luigi. - In: INORGANIC CHEMISTRY. - ISSN 0020-1669. - 58:16(2019), pp. 10616-10619-10619. [10.1021/acs.inorgchem.9b01900]

Structural Characterization of a Gold/Serum Albumin Complex

Ferraro, Giarita
Membro del Collaboration Group
;
Merlino, Antonello
Supervision
;
2019

Abstract

The medicinal gold(III) dithiocarbamato complex AuL12 forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.
2019
Structural Characterization of a Gold/Serum Albumin Complex / Pratesi, Alessandro; Cirri, Damiano; Fregona, Dolores; Ferraro, Giarita; Giorgio, Anna; Merlino, Antonello; Messori, Luigi. - In: INORGANIC CHEMISTRY. - ISSN 0020-1669. - 58:16(2019), pp. 10616-10619-10619. [10.1021/acs.inorgchem.9b01900]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/758497
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