Psoriasis prevalence is increasing among elderly subjects. Elderly psoriasis patients represent a challenge for dermatologists due to multiple comorbidities, polypharmacy, immune senescence which lead to increased possibility of adverse events, drug interactions and susceptibility to cancers and infections. Therefore, conventional systemic therapies are often contraindicated with biologics appearing as mainstay for moderate-to-severe disease. However, data on efficacy and safety of biologics in elderly are scant.
Real life efficacy and safety of secukinumab in elderly psoriasis patients over a 2-year period / Megna, M; Camela, E; Cinelli, E; Fabbrocini, G. - In: CLINICAL AND EXPERIMENTAL DERMATOLOGY. - ISSN 0307-6938. - (2020). [10.1111/ced.14258]
Real life efficacy and safety of secukinumab in elderly psoriasis patients over a 2-year period
Megna, M
;Camela, E;Cinelli, E;Fabbrocini, G
2020
Abstract
Psoriasis prevalence is increasing among elderly subjects. Elderly psoriasis patients represent a challenge for dermatologists due to multiple comorbidities, polypharmacy, immune senescence which lead to increased possibility of adverse events, drug interactions and susceptibility to cancers and infections. Therefore, conventional systemic therapies are often contraindicated with biologics appearing as mainstay for moderate-to-severe disease. However, data on efficacy and safety of biologics in elderly are scant.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.