Sayaman, Saad et al. investigate the effect of common and rare germline variants on 139 well-defined immune traits in ∼9000 cancer patients enrolled in TCGA, providing evidence for the impact of germline genetics on the composition and functional orientation of the tumor immune microenvironment.

Germline genetic contribution to the immune landscape of cancer / Sayaman, R. W.; Saad, M.; Thorsson, V.; Hu, D.; Hendrickx, W.; Roelands, J.; Porta-Pardo, E.; Mokrab, Y.; Farshidfar, F.; Kirchhoff, T.; Sweis, R. F.; Bathe, O. F.; Heimann, C.; Campbell, M. J.; Stretch, C.; Huntsman, S.; Graff, R. E.; Syed, N.; Radvanyi, L.; Shelley, S.; Wolf, D.; Marincola, F. M.; Ceccarelli, M.; Galon, J.; Ziv, E.; Bedognetti, D.. - In: IMMUNITY. - ISSN 1074-7613. - 54:2(2021), pp. 367-386.e8. [10.1016/j.immuni.2021.01.011]

Germline genetic contribution to the immune landscape of cancer

Ceccarelli M.;
2021

Abstract

Sayaman, Saad et al. investigate the effect of common and rare germline variants on 139 well-defined immune traits in ∼9000 cancer patients enrolled in TCGA, providing evidence for the impact of germline genetics on the composition and functional orientation of the tumor immune microenvironment.
2021
Germline genetic contribution to the immune landscape of cancer / Sayaman, R. W.; Saad, M.; Thorsson, V.; Hu, D.; Hendrickx, W.; Roelands, J.; Porta-Pardo, E.; Mokrab, Y.; Farshidfar, F.; Kirchhoff, T.; Sweis, R. F.; Bathe, O. F.; Heimann, C.; Campbell, M. J.; Stretch, C.; Huntsman, S.; Graff, R. E.; Syed, N.; Radvanyi, L.; Shelley, S.; Wolf, D.; Marincola, F. M.; Ceccarelli, M.; Galon, J.; Ziv, E.; Bedognetti, D.. - In: IMMUNITY. - ISSN 1074-7613. - 54:2(2021), pp. 367-386.e8. [10.1016/j.immuni.2021.01.011]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/844576
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