Extracellular vesicles are important biomarkers and therapeutic targets for breast cancer (BC). However, specific tools for their recognition are lacking. Condorelli and colleagues describe the finding of a high-affinity aptamer (ex-50.T) able to specifically target BC exosomes acting as a promising diagnostic and therapeutic tool.
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes / Esposito, C. L.; Quintavalle, C.; Ingenito, F.; Rotoli, D.; Roscigno, G.; Nuzzo, S.; Thomas, R.; Catuogno, S.; de Franciscis, V.; Condorelli, G.. - In: MOLECULAR THERAPY NUCLEIC ACIDS. - ISSN 2162-2531. - 23:(2021), pp. 982-994. [10.1016/j.omtn.2021.01.012]
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Esposito C. L.;Quintavalle C.;Ingenito F.;Roscigno G.;Thomas R.;Condorelli G.
2021
Abstract
Extracellular vesicles are important biomarkers and therapeutic targets for breast cancer (BC). However, specific tools for their recognition are lacking. Condorelli and colleagues describe the finding of a high-affinity aptamer (ex-50.T) able to specifically target BC exosomes acting as a promising diagnostic and therapeutic tool.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
