TRIM8, an E3 ubiquitin ligase and a member of TRIM family proteins, has been identified to function as both a tumor suppressor and an oncogenic molecule. Further, TRIM8 is emerging as an important player in bipolar spindle formation and mitotic progression, and its sphere of influence is growing across multiple human pathologies and cancers.
Rise of TRIM8: A Molecule of Duality / Bhaduri, U.; Merla, G.. - In: MOLECULAR THERAPY NUCLEIC ACIDS. - ISSN 2162-2531. - 22:(2020), pp. 434-444. [10.1016/j.omtn.2020.08.034]
Rise of TRIM8: A Molecule of Duality
Merla G.
2020
Abstract
TRIM8, an E3 ubiquitin ligase and a member of TRIM family proteins, has been identified to function as both a tumor suppressor and an oncogenic molecule. Further, TRIM8 is emerging as an important player in bipolar spindle formation and mitotic progression, and its sphere of influence is growing across multiple human pathologies and cancers.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
