We address the problem of controlling the dilution rate in a chemostat to regulate the ratio between the concentrations of two microbial populations growing in continuous culture. After analyzing the open-loop dynamics of this multicellular system, we present two alternative feedback control strategies, one based on a gain-scheduled state feedback controller, the other on a switching control strategy. We show that both strategies are effective in solving the problem and illustrate the results by a set of representative in-silico experiments.
Feedback Ratiometric Control of Two Microbial Populations in a Single Chemostat / Fiore, D.; Della Rossa, F.; Guarino, A.; di Bernardo, M.. - In: IEEE CONTROL SYSTEMS LETTERS. - ISSN 2475-1456. - 6:(2022), pp. 800-805. [10.1109/LCSYS.2021.3086234]
Feedback Ratiometric Control of Two Microbial Populations in a Single Chemostat
Fiore D.;Della Rossa F.;Guarino A.;di Bernardo M.
2022
Abstract
We address the problem of controlling the dilution rate in a chemostat to regulate the ratio between the concentrations of two microbial populations growing in continuous culture. After analyzing the open-loop dynamics of this multicellular system, we present two alternative feedback control strategies, one based on a gain-scheduled state feedback controller, the other on a switching control strategy. We show that both strategies are effective in solving the problem and illustrate the results by a set of representative in-silico experiments.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
