Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.
Atrial myxomas arise from multipotent cardiac stem cells / Scalise, M., Torella, M., Marino, F., Ravo, M., Giurato, G., Vicinanza, C., Cianflone, E., Mancuso, T., Aquila, I., Salerno, L., Nassa, G., Agosti, V., De Angelis, A., Urbanek, K., Berrino, L., Veltri, P., Paolino, D., Mastroroberto, P., De Feo, M., Viglietto, G., et al.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - (2020). [10.1093/eurheartj/ehaa156]
Atrial myxomas arise from multipotent cardiac stem cells
Urbanek, K.;Viglietto, G.;Torella, D.
2020
Abstract
Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.| File | Dimensione | Formato | |
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