Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.
Atrial myxomas arise from multipotent cardiac stem cells / Scalise, M.; Torella, M.; Marino, F.; Ravo, M.; Giurato, G.; Vicinanza, C.; Cianflone, E.; Mancuso, T.; Aquila, I.; Salerno, L.; Nassa, G.; Agosti, V.; De Angelis, A.; Urbanek, K.; Berrino, L.; Veltri, P.; Paolino, D.; Mastroroberto, Pasquale; De Feo, Marisa; Viglietto, G.; Weisz, A.; Nadal-Ginard, B.; Ellison-Hughes, G. M; Torella, D.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - (2020). [10.1093/eurheartj/ehaa156]
Atrial myxomas arise from multipotent cardiac stem cells
Urbanek, K.;Viglietto, G.;Torella, D.
2020
Abstract
Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.File | Dimensione | Formato | |
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