In this work, two different bioheat models are implemente d to model a thermal ablation of hepatocellular carcinoma liver tumor . A mixed constant and pulsating heat source protocol is developed, evaluating the thermal damage level on the tumor rim. A porous media based model and a modified Pennes’ bioheat equation are developed to consider the realistic variation of both blood volume fraction (porosity) in the first model, and perfusion term in the second one , from tumor core, tumor rim, and the sur rounding healthy tissue. The results are presented in terms of temperature fields, thermal damage and dimension of the ablated zone achieved.
MODELING A THERMAL DAMAGE CONTROLLED PROTOCOL FOR LIVER TUMOR THERMAL ABLATION : A COMPARISON BETWEEN TWO BIOHEAT MODELS / Andreozzi, Assunta; Brunese, Luca; Iasiello, Marcello; Tucci, Claudio; Peter Vanoli, Giuseppe. - (2022).
MODELING A THERMAL DAMAGE CONTROLLED PROTOCOL FOR LIVER TUMOR THERMAL ABLATION : A COMPARISON BETWEEN TWO BIOHEAT MODELS
Assunta Andreozzi;Marcello Iasiello
;
2022
Abstract
In this work, two different bioheat models are implemente d to model a thermal ablation of hepatocellular carcinoma liver tumor . A mixed constant and pulsating heat source protocol is developed, evaluating the thermal damage level on the tumor rim. A porous media based model and a modified Pennes’ bioheat equation are developed to consider the realistic variation of both blood volume fraction (porosity) in the first model, and perfusion term in the second one , from tumor core, tumor rim, and the sur rounding healthy tissue. The results are presented in terms of temperature fields, thermal damage and dimension of the ablated zone achieved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.