In solid organ transplant recipients, COVID-19 is associated with a poor prognosis because of immunosuppression. Some studies suggest a potential therapeutic role of mammalian Target of Rapamycin (mTOR) inhibitors in SARS-CoV-2 infection. This study aimed to assess the impact of mTOR employment on the evolution and outcome of SARS-CoV-2 infection in solid organ transplant recipients.
mTOR Inhibitor Use Is Associated With a Favorable Outcome of COVID-19 in Patients of Kidney Transplant: Results of a Retrospective Study / Pinchera, B.; Spirito, L.; Buonomo, A. R.; Foggia, M.; Carrano, R.; Salemi, F.; Schettino, E.; Papa, F.; La Rocca, R.; Crocetto, F.; Napolitano, L.; Villari, R.; Gentile, I.. - In: FRONTIERS IN MEDICINE. - ISSN 2296-858X. - 9:(2022), pp. 1-6. [10.3389/fmed.2022.852973]
mTOR Inhibitor Use Is Associated With a Favorable Outcome of COVID-19 in Patients of Kidney Transplant: Results of a Retrospective Study
Pinchera B.;Buonomo A. R.;Papa F.;La Rocca R.;Crocetto F.;Villari R.;Gentile I.
2022
Abstract
In solid organ transplant recipients, COVID-19 is associated with a poor prognosis because of immunosuppression. Some studies suggest a potential therapeutic role of mammalian Target of Rapamycin (mTOR) inhibitors in SARS-CoV-2 infection. This study aimed to assess the impact of mTOR employment on the evolution and outcome of SARS-CoV-2 infection in solid organ transplant recipients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
