Bence Jones proteinuria (BJP) refers to monoclonal free immunoglobulin light chains detected in urine, deriving from the clonal expansion of plasma cells in the bone marrow in patients with plasma cell dyscrasias, associated with monoclonal gammopathies of uncertain origin. This review summarizes routinely diagnostic procedures to assess BJP highlighting critical steps of pre-analytical, analytical, and post-analytical phases.
The dark side of current analytic methods for Bence Jones Proteinuria / Natali, P; Cigliana, G; Napodano, C; Basile, V; Debbia, D; Pocino, K; Savoia, M; Marino, M; Gulli, F; Basile, U. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 2284-0729. - 26:18(2022), pp. 6777-6786. [10.26355/eurrev_202209_29779]
The dark side of current analytic methods for Bence Jones Proteinuria
Savoia, M;
2022
Abstract
Bence Jones proteinuria (BJP) refers to monoclonal free immunoglobulin light chains detected in urine, deriving from the clonal expansion of plasma cells in the bone marrow in patients with plasma cell dyscrasias, associated with monoclonal gammopathies of uncertain origin. This review summarizes routinely diagnostic procedures to assess BJP highlighting critical steps of pre-analytical, analytical, and post-analytical phases.| File | Dimensione | Formato | |
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