Systemic biomarkers for severity of SARS-CoV-2 infection are of great interest. In this study, we evaluated a set of collagen metabolites and extracellular matrix remodeling biomarkers including procollagen type III amino terminal propeptide (PIIINP), tissue inhibitor of metalloproteinases 1 (TIMP-1) and hyaluronic acid (HA) as prognostic indicators in COVID-19 patients.
Circulating tissue inhibitor of metalloproteinases 1 (TIMP-1) at COVID-19 onset predicts severity status / Brusa, Stefano; Terracciano, Daniela; Bruzzese, Dario; Fiorenza, Mariano; Stanziola, Lucia; Pinchera, Biagio; Valente, Valeria; Gentile, Ivan; Cittadini, Antonio; Mormile, Ilaria; Mormile, Mauro; Portella, Giuseppe. - In: FRONTIERS IN MEDICINE. - ISSN 2296-858X. - 9:(2022), p. 1034288. [10.3389/fmed.2022.1034288]
Circulating tissue inhibitor of metalloproteinases 1 (TIMP-1) at COVID-19 onset predicts severity status
Brusa, Stefano;Terracciano, Daniela;Bruzzese, Dario;Pinchera, Biagio;Valente, Valeria;Gentile, Ivan;Cittadini, Antonio;Mormile, Ilaria;Mormile, Mauro;Portella, Giuseppe
2022
Abstract
Systemic biomarkers for severity of SARS-CoV-2 infection are of great interest. In this study, we evaluated a set of collagen metabolites and extracellular matrix remodeling biomarkers including procollagen type III amino terminal propeptide (PIIINP), tissue inhibitor of metalloproteinases 1 (TIMP-1) and hyaluronic acid (HA) as prognostic indicators in COVID-19 patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
