Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber

Grasso, S.; Varallo, A.; Ricciardi, R.; Italiano, M. E.; Oliviero, C.; D'Avino, V.; Feoli, C.; Ambrosino, F.; Pugliese, M.; Clemente, S.

doi:10.1016/j.apradiso.2023.110981

: Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25-50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three different dosimetric systems. Results showed a dosimetric accuracy of the ionization chamber together with the Alanine dosimeter. TLDs measurements exhibited a small overestimation by 4% of the absorbed dose. The Dose Uniformity Ratio (DUR), between maximum and minimum dose levels in the canister, was in good agreement with the manufacturer specifications (≤1.5).

Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber / Grasso, S.; Varallo, A.; Ricciardi, R.; Italiano, M. E.; Oliviero, C.; D'Avino, V.; Feoli, C.; Ambrosino, F.; Pugliese, M.; Clemente, S.. - In: APPLIED RADIATION AND ISOTOPES. - ISSN 1872-9800. - 200:(2023), p. 110981. [10.1016/j.apradiso.2023.110981]