Objectives Formulas made from hydrolyzed rice proteins (HRPF) are well-tolerated plant-based alternatives to cow's milk protein (CMP)-based formulas for the dietary management of paediatric patients with CMP allergy (CMPA). Growth in patients with CMPA fed with HRPF has been evaluated in several studies with conflicting results. The aim was to evaluate the growth pattern of children with CMPA over a 12-month follow-up period. Methods Prospective cohort study evaluating growth patterns in challenge proven CMPA paediatric patients receiving HRPF for 12 months. Outcomes were anthropometry (body weight, body length, head circumference), adherence to the study formula and occurrence of adverse events (AEs). Results Sixty-six children were included and completed the 12-month study. At baseline, all CMPA patients were weaned. For the entire CMPA pediatric patients' cohort, from baseline to the end of the study period, the growth pattern resulted within the normal range of WHO growth references. The formula was well tolerated. Adherence was optimal and no AEs related to HRPF use were reported. Conclusions HRPF is well tolerated and can help support healthy growth and development in infants and young children with CMPA. These type of formula can be given with complementary foods in the dietary management of CMPA.

Growth pattern of paediatric patients affected by cow milk protein allergy fed with rice hydrolyzed formula / Nocerino, Rita; Coppola, Serena; Carucci, Laura; Oglio, Franca; Cozzolino, Marica; Masino, Antonio; Ozen, Gulsum; Farnetano, Margherita; Berni Canani, Roberto. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - (2024). [10.1002/jpn3.12161]

Growth pattern of paediatric patients affected by cow milk protein allergy fed with rice hydrolyzed formula

Nocerino, Rita;Coppola, Serena;Carucci, Laura;Oglio, Franca;Cozzolino, Marica;Masino, Antonio;Farnetano, Margherita;Berni Canani, Roberto
2024

Abstract

Objectives Formulas made from hydrolyzed rice proteins (HRPF) are well-tolerated plant-based alternatives to cow's milk protein (CMP)-based formulas for the dietary management of paediatric patients with CMP allergy (CMPA). Growth in patients with CMPA fed with HRPF has been evaluated in several studies with conflicting results. The aim was to evaluate the growth pattern of children with CMPA over a 12-month follow-up period. Methods Prospective cohort study evaluating growth patterns in challenge proven CMPA paediatric patients receiving HRPF for 12 months. Outcomes were anthropometry (body weight, body length, head circumference), adherence to the study formula and occurrence of adverse events (AEs). Results Sixty-six children were included and completed the 12-month study. At baseline, all CMPA patients were weaned. For the entire CMPA pediatric patients' cohort, from baseline to the end of the study period, the growth pattern resulted within the normal range of WHO growth references. The formula was well tolerated. Adherence was optimal and no AEs related to HRPF use were reported. Conclusions HRPF is well tolerated and can help support healthy growth and development in infants and young children with CMPA. These type of formula can be given with complementary foods in the dietary management of CMPA.
2024
Growth pattern of paediatric patients affected by cow milk protein allergy fed with rice hydrolyzed formula / Nocerino, Rita; Coppola, Serena; Carucci, Laura; Oglio, Franca; Cozzolino, Marica; Masino, Antonio; Ozen, Gulsum; Farnetano, Margherita; Berni Canani, Roberto. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - (2024). [10.1002/jpn3.12161]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/955585
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