IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
NA - Nord America 2.368
EU - Europa 1.900
AS - Asia 714
AF - Africa 60
SA - Sud America 10
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.054
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Nazione #
US - Stati Uniti d'America 2.333
IT - Italia 927
SG - Singapore 364
DE - Germania 294
CN - Cina 262
NL - Olanda 139
FR - Francia 120
UA - Ucraina 95
IE - Irlanda 94
FI - Finlandia 88
CI - Costa d'Avorio 55
GB - Regno Unito 41
SE - Svezia 37
VN - Vietnam 37
CA - Canada 34
IN - India 17
ES - Italia 15
IR - Iran 11
JP - Giappone 11
PL - Polonia 11
BG - Bulgaria 10
BR - Brasile 8
TR - Turchia 7
AT - Austria 6
GR - Grecia 6
EG - Egitto 4
SK - Slovacchia (Repubblica Slovacca) 4
BE - Belgio 3
CH - Svizzera 3
CL - Cile 2
EU - Europa 2
SI - Slovenia 2
CZ - Repubblica Ceca 1
HK - Hong Kong 1
ID - Indonesia 1
JM - Giamaica 1
KR - Corea 1
LT - Lituania 1
MA - Marocco 1
MY - Malesia 1
NO - Norvegia 1
PH - Filippine 1
RS - Serbia 1
RU - Federazione Russa 1
Totale 5.054
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Città #
Chandler 433
Singapore 309
Ashburn 288
Naples 233
Amsterdam 130
Jacksonville 117
Napoli 113
Millbury 90
Menlo Park 76
Princeton 74
Beijing 72
Nanjing 64
Santa Clara 59
Krefeld 57
Boston 49
Wilmington 46
Houston 38
Woodbridge 38
Dong Ket 36
Des Moines 35
Ottawa 31
Lawrence 26
Bad Bellingen 25
Dearborn 21
Nanchang 21
San Giorgio a Cremano 20
Salerno 19
Milan 18
Pozzuoli 18
Redwood City 17
Rome 17
Nuremberg 16
Mugnano di Napoli 15
Falls Church 14
Hebei 14
Trieste 12
Jiaxing 11
Norwalk 11
Cambridge 10
Shenyang 10
Tianjin 10
Dublin 9
Indiana 9
Scunthorpe 9
Sofia 9
Ardabil 8
Dallas 8
Formia 8
Roccarainola 8
Ann Arbor 7
Helsinki 7
Kronberg 7
Zola Predosa 7
Athens 6
Boardman 6
Changsha 6
Falcone 6
Jena 6
Krakow 6
Kunming 6
Lappeenranta 6
Los Angeles 6
Pune 6
Rho 6
Afragola 5
Bari 5
Caserta 5
Council Bluffs 5
Ercolano 5
Vienna 5
Augusta 4
Bratislava 4
Casoria 4
Frankfurt am Main 4
Fucecchio 4
Hangzhou 4
Santiago De Compostela 4
Shenzhen 4
São Paulo 4
Vallo della Lucania 4
Avellino 3
Aversa 3
Bacoli 3
Bologna 3
Castel Volturno 3
Doshin 3
Fairfield 3
Florence 3
Gallarate 3
Giugliano in Campania 3
Guangzhou 3
Hebi 3
Livorno 3
Lucca 3
Madrid 3
Marigliano 3
Minerbio 3
Munich 3
Orange 3
Padenghe sul Garda 3
Totale 3.005
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 318
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 203
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 182
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 102
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 82
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 79
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 74
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 74
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 69
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 68
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 68
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 66
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 65
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 64
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 60
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 58
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 58
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 58
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 58
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 57
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 56
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 55
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 54
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 54
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 53
A valuable synthesis of reduced peptide bond by microwave irradiation 52
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 51
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 51
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 50
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 50
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 49
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 48
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 48
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 48
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 48
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 48
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 48
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 47
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 46
Basal nitric oxide modulates vascular effects of a peptide activating protease activated receptor 2 46
Identification of a pepducin acting as S1P3 receptor antagonist 46
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 46
Montelukast salts and pharmaceutical compositions containing the same 46
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 44
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives 44
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 43
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 43
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 43
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 43
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 42
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 41
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 40
Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage 40
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 40
A hydrogen sulfide-releasing dexamethasone derivative attenuates atopic dermatitis severity signs and the associated oxidative stress markers in mice 40
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 39
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 39
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 39
Pharmacokinetic profile of atenolol aspirinate 38
Thrombin receptors and their antagonists: an update on the patent literature 38
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 38
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 38
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 38
Effects of N- and C-terminal addition of oligolysines or native loop residues on the biophysical properties of transmembrane domain peptides from a G-protein coupled receptor 37
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 36
Novel tools for the elucidation of physio-pathological role of H2S 36
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 36
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 35
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands 35
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 35
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 34
Design and synthesis of potential b-sheet nucleatorsvia Suzuki coupling reaction 34
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 34
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 34
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 33
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 33
Synthesis of benzamide derivatives and their evaluation as antiprion agents 33
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 33
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 32
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 31
Quantification of 3α-hydroxytibolone in human plasma by high performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS): Application in a bioequivalence study in healthy postmenopausal volunteers 31
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 31
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 31
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 30
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 29
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 29
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 28
Synthesis and in vitro pharmacological evaluation of a new series of 5-HT1A 5-HT2A and 5-HT2C receptor ligands containing a norbornene nucleus. 28
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 27
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 27
H2s donors and their use in medicinal chemistry 27
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 26
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 26
Efficient microwave-assisted synthesis of 4-amino-2-benzazepin-3-ones as conformationally restricted dipeptide mimetics 25
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 25
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 25
New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: Synthesis and in vitro pharmacological evaluation 25
Synthesis and pharmacological evaluation of peptide-mimetic protease-activated receptor-1 antagonists containing novel heterocyclic scaffolds 24
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 24
Design of inhibitors for human tissue kallikrein using non-natural aromatic and basic amino acids. 24
Totale 4.936
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Categoria #
all - tutte 21.816
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.816
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020324 0 0 0 0 70 44 32 11 13 38 58 58
2020/2021386 22 28 22 24 44 29 40 12 39 12 51 63
2021/2022845 4 3 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/2025571 168 194 50 83 76 0 0 0 0 0 0 0
Totale 5.309