IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
NA - Nord America 5.694
AS - Asia 5.180
EU - Europa 4.803
SA - Sud America 611
Continente sconosciuto - Info sul continente non disponibili 282
AF - Africa 179
OC - Oceania 6
Totale 16.755
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Nazione #
US - Stati Uniti d'America 5.478
SG - Singapore 2.232
RU - Federazione Russa 1.781
IT - Italia 1.327
CN - Cina 1.040
VN - Vietnam 970
DE - Germania 471
BR - Brasile 468
HK - Hong Kong 361
FR - Francia 286
NL - Olanda 183
FI - Finlandia 167
GB - Regno Unito 125
CA - Canada 122
BD - Bangladesh 113
UA - Ucraina 112
IE - Irlanda 100
JP - Giappone 92
IN - India 90
CI - Costa d'Avorio 56
ES - Italia 51
AR - Argentina 49
SE - Svezia 48
MX - Messico 43
ZA - Sudafrica 42
PL - Polonia 40
KR - Corea 33
EC - Ecuador 29
GR - Grecia 27
PH - Filippine 27
MA - Marocco 25
ID - Indonesia 24
IQ - Iraq 22
TH - Thailandia 22
TR - Turchia 20
CO - Colombia 19
PK - Pakistan 18
AT - Austria 16
VE - Venezuela 16
JM - Giamaica 13
BG - Bulgaria 12
IR - Iran 12
LT - Lituania 12
TW - Taiwan 11
EG - Egitto 10
IL - Israele 10
JO - Giordania 10
PY - Paraguay 10
SA - Arabia Saudita 10
UZ - Uzbekistan 10
CL - Cile 9
MY - Malesia 9
TN - Tunisia 9
BE - Belgio 8
NI - Nicaragua 7
AE - Emirati Arabi Uniti 6
AZ - Azerbaigian 5
CH - Svizzera 5
DZ - Algeria 5
HN - Honduras 5
KE - Kenya 5
LB - Libano 5
UY - Uruguay 5
AU - Australia 4
CR - Costa Rica 4
KZ - Kazakistan 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
AL - Albania 3
AO - Angola 3
BA - Bosnia-Erzegovina 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
GT - Guatemala 3
NP - Nepal 3
PE - Perù 3
SI - Slovenia 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
AM - Armenia 2
BO - Bolivia 2
BS - Bahamas 2
CZ - Repubblica Ceca 2
DM - Dominica 2
EU - Europa 2
GA - Gabon 2
GE - Georgia 2
GN - Guinea 2
HU - Ungheria 2
KG - Kirghizistan 2
KW - Kuwait 2
LV - Lettonia 2
MG - Madagascar 2
MN - Mongolia 2
NO - Norvegia 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
RS - Serbia 2
Totale 16.444
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Città #
Singapore 1.101
San Jose 936
Ashburn 609
Chandler 434
Moscow 417
Naples 406
Beijing 357
Hong Kong 343
Ho Chi Minh City 267
Santa Clara 229
Hanoi 208
Council Bluffs 186
Amsterdam 149
Los Angeles 127
Hefei 124
The Dalles 121
Jacksonville 120
Napoli 113
Lauterbourg 112
Millbury 90
Menlo Park 76
Princeton 74
Tokyo 71
Munich 67
New York 67
Nanjing 65
São Paulo 65
Boston 57
Krefeld 57
Buffalo 53
Houston 53
Dallas 52
Phoenix 49
Wilmington 46
Haiphong 43
Milan 43
Frankfurt am Main 42
Helsinki 41
Redondo Beach 41
Da Nang 39
Turku 39
Woodbridge 38
Rome 37
Dong Ket 36
Ottawa 36
Des Moines 35
Falkenstein 33
Nuremberg 32
Brooklyn 29
Orem 29
Toronto 28
London 27
Lawrence 26
Bad Bellingen 25
Chicago 25
Atlanta 23
Mexico City 23
Warsaw 23
Seoul 22
Dearborn 21
Johannesburg 21
Nanchang 21
Salerno 21
San Giorgio a Cremano 20
Casablanca 19
Denver 19
Pozzuoli 18
Seattle 18
Thessaloniki 18
Montreal 17
Redwood City 17
Chennai 16
Tianjin 16
Hải Dương 15
Mugnano di Napoli 15
Rio de Janeiro 15
Dublin 14
Falls Church 14
Hebei 14
Manchester 14
Stockholm 14
Norwalk 13
San Francisco 13
Jiaxing 12
Shenyang 12
Trieste 12
Lappeenranta 11
Biên Hòa 10
Cambridge 10
Can Tho 10
Memphis 10
New Delhi 10
Philadelphia 10
Sofia 10
Bangkok 9
Bologna 9
Cervino 9
Guangzhou 9
Indiana 9
Mumbai 9
Totale 8.690
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 395
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 366
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 304
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives 246
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 216
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 213
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 199
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 195
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 194
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 187
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 178
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 176
Identification of a pepducin acting as S1P3 receptor antagonist 173
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 173
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 171
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 169
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 166
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 166
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 164
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 163
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 162
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 162
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 158
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 158
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 157
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 156
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 155
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 155
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 155
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 155
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 153
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 150
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 149
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 148
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 148
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 148
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 146
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 146
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 144
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 144
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 144
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 140
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 140
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 140
Novel tools for the elucidation of physio-pathological role of H2S 138
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 138
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 137
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 137
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 136
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 136
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 136
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 135
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 134
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 134
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 133
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 133
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 131
Synthesis of benzamide derivatives and their evaluation as antiprion agents 131
H2s donors and their use in medicinal chemistry 131
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 130
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 129
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 129
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 128
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 128
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 126
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 125
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 124
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 124
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 122
Thrombin receptors and their antagonists: an update on the patent literature 121
The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism 120
A valuable synthesis of reduced peptide bond by microwave irradiation 120
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 118
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 118
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 117
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes 117
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 116
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 116
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 115
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 115
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 114
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 114
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 113
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 112
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 112
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 111
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 111
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 110
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 110
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 109
Minimal structural requirements for agonist activity of PAR-2 activating peptides. 108
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 108
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 108
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 108
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 105
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 105
Pills of Multi-Target H2S Donating Molecules for Complex Diseases 105
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 104
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 103
Microwave-enhanced solution coupling of the a,a-dialkyl amino acid, Aib 101
Totale 14.576
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Categoria #
all - tutte 55.377
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.377
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022838 0 0 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/20253.918 168 194 50 83 94 266 359 274 220 460 1.440 310
2025/20267.288 758 465 794 609 1.272 257 842 374 969 505 242 201
2026/2027811 172 422 217 0 0 0 0 0 0 0 0 0
Totale 16.755