IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
AS - Asia 5.155
NA - Nord America 5.063
EU - Europa 4.744
SA - Sud America 599
AF - Africa 176
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 15.745
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Nazione #
US - Stati Uniti d'America 4.874
SG - Singapore 2.228
RU - Federazione Russa 1.781
IT - Italia 1.280
CN - Cina 1.035
VN - Vietnam 968
DE - Germania 471
BR - Brasile 464
HK - Hong Kong 360
FR - Francia 286
NL - Olanda 182
FI - Finlandia 167
GB - Regno Unito 119
UA - Ucraina 112
CA - Canada 107
BD - Bangladesh 106
IE - Irlanda 99
JP - Giappone 92
IN - India 90
CI - Costa d'Avorio 56
ES - Italia 51
SE - Svezia 48
AR - Argentina 47
ZA - Sudafrica 42
MX - Messico 41
PL - Polonia 40
KR - Corea 33
EC - Ecuador 27
GR - Grecia 26
MA - Marocco 25
PH - Filippine 25
ID - Indonesia 22
IQ - Iraq 22
TH - Thailandia 21
TR - Turchia 20
PK - Pakistan 18
AT - Austria 16
CO - Colombia 16
VE - Venezuela 15
BG - Bulgaria 12
IR - Iran 12
LT - Lituania 12
TW - Taiwan 11
EG - Egitto 10
IL - Israele 10
JO - Giordania 10
PY - Paraguay 10
UZ - Uzbekistan 10
CL - Cile 9
MY - Malesia 9
SA - Arabia Saudita 9
TN - Tunisia 9
JM - Giamaica 8
BE - Belgio 7
AE - Emirati Arabi Uniti 6
AZ - Azerbaigian 5
CH - Svizzera 5
DZ - Algeria 5
LB - Libano 5
NI - Nicaragua 5
UY - Uruguay 5
AU - Australia 4
CR - Costa Rica 4
HN - Honduras 4
KE - Kenya 4
KZ - Kazakistan 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
AO - Angola 3
BA - Bosnia-Erzegovina 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
NP - Nepal 3
PE - Perù 3
SI - Slovenia 3
TT - Trinidad e Tobago 3
AL - Albania 2
AM - Armenia 2
BO - Bolivia 2
BS - Bahamas 2
CZ - Repubblica Ceca 2
DM - Dominica 2
EU - Europa 2
GA - Gabon 2
GE - Georgia 2
GN - Guinea 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
KW - Kuwait 2
LV - Lettonia 2
MG - Madagascar 2
MN - Mongolia 2
NO - Norvegia 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SN - Senegal 2
SV - El Salvador 2
Totale 15.717
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Città #
Singapore 1.100
San Jose 789
Ashburn 582
Chandler 434
Moscow 417
Naples 379
Beijing 356
Hong Kong 342
Ho Chi Minh City 267
Santa Clara 211
Hanoi 206
Amsterdam 149
Hefei 124
Los Angeles 123
The Dalles 121
Jacksonville 119
Napoli 113
Lauterbourg 112
Millbury 90
Menlo Park 76
Princeton 74
Tokyo 71
Council Bluffs 68
Munich 67
Nanjing 65
São Paulo 63
New York 62
Krefeld 57
Boston 56
Buffalo 52
Houston 50
Wilmington 46
Dallas 44
Haiphong 43
Frankfurt am Main 42
Helsinki 41
Redondo Beach 41
Da Nang 39
Milan 39
Turku 39
Woodbridge 38
Dong Ket 36
Des Moines 35
Ottawa 35
Rome 35
Falkenstein 33
Nuremberg 32
Orem 28
Brooklyn 27
Toronto 27
Lawrence 26
Bad Bellingen 25
London 25
Chicago 23
Warsaw 23
Mexico City 22
Seoul 22
Dearborn 21
Johannesburg 21
Nanchang 21
Salerno 21
Atlanta 20
San Giorgio a Cremano 20
Casablanca 19
Pozzuoli 18
Seattle 18
Thessaloniki 18
Redwood City 17
Chennai 16
Denver 16
Montreal 16
Phoenix 16
Tianjin 16
Hải Dương 15
Mugnano di Napoli 15
Rio de Janeiro 15
Dublin 14
Falls Church 14
Hebei 14
Stockholm 14
Manchester 13
San Francisco 13
Jiaxing 12
Norwalk 12
Shenyang 12
Trieste 12
Lappeenranta 11
Biên Hòa 10
Cambridge 10
Can Tho 10
New Delhi 10
Sofia 10
Cervino 9
Guangzhou 9
Indiana 9
Mumbai 9
Poplar 9
Scunthorpe 9
Vienna 9
Amman 8
Totale 8.262
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 393
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 360
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 302
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 205
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 200
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 195
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 188
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 181
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 179
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 173
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 172
Identification of a pepducin acting as S1P3 receptor antagonist 170
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 168
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 166
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 163
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 162
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 161
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 160
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 160
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 158
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 155
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 154
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 154
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 153
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 152
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 151
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 149
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 148
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 148
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 146
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 145
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 144
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 143
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 143
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 142
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 141
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 141
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 139
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 138
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 137
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 137
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 137
Novel tools for the elucidation of physio-pathological role of H2S 136
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 135
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 135
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 135
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 133
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 132
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 132
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 130
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 130
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 130
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 128
Synthesis of benzamide derivatives and their evaluation as antiprion agents 128
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 128
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 127
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 127
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 127
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 125
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 123
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 123
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 123
H2s donors and their use in medicinal chemistry 123
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 122
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 122
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 120
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 120
A valuable synthesis of reduced peptide bond by microwave irradiation 118
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 117
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 115
Thrombin receptors and their antagonists: an update on the patent literature 115
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 115
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 115
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 113
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 113
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 112
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 112
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 111
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 111
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes 110
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 109
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 109
The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism 108
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 108
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 108
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 108
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 107
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 107
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 107
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 106
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 105
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 103
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 102
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 102
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 101
Minimal structural requirements for agonist activity of PAR-2 activating peptides. 101
Pills of Multi-Target H2S Donating Molecules for Complex Diseases 100
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 99
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 99
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 98
Totale 13.971
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Categoria #
all - tutte 50.973
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.973
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022845 4 3 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/20253.918 168 194 50 83 94 266 359 274 220 460 1.440 310
2025/20267.288 758 465 794 609 1.272 257 842 374 969 505 242 201
2026/202780 80 0 0 0 0 0 0 0 0 0 0 0
Totale 16.024