IRIS
D'ALESSIO, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 5.300
NA - Nord America 5.259
EU - Europa 3.737
SA - Sud America 648
AF - Africa 129
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 6
Totale 15.086
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Nazione #
US - Stati Uniti d'America 5.044
SG - Singapore 2.401
RU - Federazione Russa 1.696
VN - Vietnam 1.081
CN - Cina 907
BR - Brasile 512
IT - Italia 445
HK - Hong Kong 395
UA - Ucraina 286
DE - Germania 244
FR - Francia 223
FI - Finlandia 208
IE - Irlanda 196
CA - Canada 132
JP - Giappone 120
NL - Olanda 120
SE - Svezia 107
GB - Regno Unito 105
IN - India 88
AR - Argentina 47
MX - Messico 47
BD - Bangladesh 41
PL - Polonia 36
ZA - Sudafrica 36
PH - Filippine 31
CI - Costa d'Avorio 30
TR - Turchia 27
EC - Ecuador 26
IQ - Iraq 26
KR - Corea 25
TW - Taiwan 25
TH - Thailandia 24
CO - Colombia 20
ES - Italia 20
ID - Indonesia 19
PK - Pakistan 18
VE - Venezuela 11
CL - Cile 10
UZ - Uzbekistan 10
DZ - Algeria 9
EG - Egitto 9
PY - Paraguay 8
SA - Arabia Saudita 8
AT - Austria 7
TN - Tunisia 7
EU - Europa 6
HN - Honduras 6
BE - Belgio 5
ET - Etiopia 5
JM - Giamaica 5
KE - Kenya 5
KZ - Kazakistan 5
PE - Perù 5
PS - Palestinian Territory 5
SN - Senegal 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
AO - Angola 4
CR - Costa Rica 4
DO - Repubblica Dominicana 4
JO - Giordania 4
LB - Libano 4
LT - Lituania 4
MA - Marocco 4
MY - Malesia 4
UY - Uruguay 4
AU - Australia 3
AZ - Azerbaigian 3
BH - Bahrain 3
BZ - Belize 3
EE - Estonia 3
IR - Iran 3
KG - Kirghizistan 3
LU - Lussemburgo 3
LV - Lettonia 3
MD - Moldavia 3
NG - Nigeria 3
OM - Oman 3
SY - Repubblica araba siriana 3
BO - Bolivia 2
BY - Bielorussia 2
CH - Svizzera 2
DK - Danimarca 2
HT - Haiti 2
HU - Ungheria 2
LY - Libia 2
MK - Macedonia 2
NI - Nicaragua 2
NP - Nepal 2
PA - Panama 2
PG - Papua Nuova Guinea 2
PT - Portogallo 2
RO - Romania 2
TT - Trinidad e Tobago 2
YT - Mayotte 2
AM - Armenia 1
BB - Barbados 1
BJ - Benin 1
BM - Bermuda 1
BS - Bahamas 1
Totale 15.059
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Città #
Singapore 1.021
San Jose 667
Chandler 597
Moscow 431
Hong Kong 383
Ashburn 325
Ho Chi Minh City 312
Jacksonville 276
Beijing 267
Hanoi 236
Millbury 211
The Dalles 201
Princeton 167
Lauterbourg 151
Santa Clara 151
Los Angeles 150
Amsterdam 110
Naples 106
Tokyo 106
Buffalo 82
Ottawa 78
Nanjing 77
Wilmington 72
Boston 70
New York 66
Munich 57
Houston 53
Hefei 50
Redondo Beach 48
Da Nang 45
São Paulo 44
Napoli 43
Woodbridge 39
Dallas 38
Cagliari 36
Haiphong 36
Frankfurt am Main 33
Seattle 30
Warsaw 30
Dearborn 29
Nanchang 27
Mexico City 26
Chicago 25
Denver 25
Kronberg 25
Shenyang 25
Orange 24
Ann Arbor 23
Brooklyn 23
Falls Church 23
Changsha 22
Montreal 22
Orem 22
Norwalk 21
Tianjin 21
Boardman 20
Milan 20
Rio de Janeiro 20
Turku 20
Atlanta 19
Helsinki 19
Johannesburg 18
London 18
Poplar 18
San Francisco 18
Kunming 17
Stockholm 17
Pune 16
Chennai 15
Manchester 15
Treviso 15
Phoenix 14
Thái Nguyên 14
Belo Horizonte 13
Hải Dương 13
Quito 12
Rome 12
Ankara 11
Campinas 11
Düsseldorf 11
Hangzhou 11
Mumbai 11
Bangkok 10
Guangzhou 10
Jinan 10
Ninh Bình 10
Tashkent 10
Baghdad 9
Bắc Ninh 9
Can Tho 9
Jiaxing 9
Quận Ba 9
Council Bluffs 8
Curitiba 8
Fortaleza 8
Guarulhos 8
Salvador 8
Washington 8
Bologna 7
Dhaka 7
Totale 7.853
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Nome #
PHYSICO-CHEMICAL CHARACTERZATION OF GEODIN: A NEW B, G- CRYSTALLINE- TYPE PROTEIN SPONGE 171
Ribonucleases and angiogenins from fish. 162
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish 156
CYTOSOLIC RNASE INHIBITOR ONLY AFFECTS RNASES WITH INTRINSIC CYTOTOXICITY. 150
3D domain swapping and protein aggregation 150
Immunotoxins and ImmunoRNases 147
Effects of a human compact anti-ErbB2 antibody on prostate cancer 144
Antitumor pancreatic-type RNases 140
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 137
Mechanisms of cardiotoxicity associated with ErbB2 inhibitors. 136
Human Antitumor RNases and ImmunoRNases 135
Full antitumor action of recombinant seminal ribonuclease depends on the removal of its N-terminal methionine 134
Effects of protein RNase inhibitor and substrate on the quaternary structures of bovine seminal RNase 133
Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors. 133
The molecular basis for the production of an antitumor protein 133
3D domain swapping and supramolecular assembly 132
Anti-ErbB2 human Immunoagents 132
Protein engineering of ribonucleases 132
ON THE THERMAL STABILITY OF THE TWO DIMERIC FORMS OF RIBONUCLEASE A. 131
Ribonucleasi Pancreatica e Seminale della Specie Bovina 131
The singular case of seminal RNase, a dimer with two quaternary conformations, inspected with Trypsin as a conformational probe 128
The antitumor action of seminal ribonuclease and its quaternary conformations 127
Anti-ErbB2 immunoagents 126
Anti-ErbB2 Human Immunoagents 126
Ribonucleases with angiogenic and bactericidal activities from the Atlantic salmon 126
A dimeric mutant of human pancreas ribonuclease with selective antitumor action 125
Intracellular route and mechanism of action of ERB-hRNase, a human anti-ErbB2 anticancer immunoagent. 123
Anti-ErbB2 human immunoagents 121
Bovine Seminal RNase: an atypical member of the ribonuclease superfamily 120
A Novel Human Anti-tumor Dimeric ImmunoRNase 119
The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis 117
A novel ErbB2 epitope targeted by human antitumor immunoagents 116
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin 116
IMMUNORNASES AS ANTITUMOUR AGENTS 116
Human, Anti-ErbB2 Antitumor Immunoagents 116
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis 114
Site-directed mutagenesis induces domain swapping and fibril formation in human pancreatic ribonuclease 114
1H and 15N sequential assignment and secondary structure of the monomeric N67D mutant of bovine seminal ribonuclease 113
A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours. 112
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 111
Muteins of pancreatic ribonuclease and uses thereof 110
A new mutein of RNase A with enhanced antitumor action 110
Bovine seminal ribonuclease, a problem protein 109
Differential binding of human immunoagents and Herceptin to the ErbB2 receptor 109
Seminal RNAase and Other RISBASES 108
A novel method for detection of seleno-methionine incorporation in protein crystals via Raman microscopy 107
A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent 106
Combinatorial experimental protocols for Erbicin-derived immunoagents and Herceptin 105
Domain swapping and protein fibril assembly 105
Investigating site-site interaction of BS-RNase by protein engineering 105
A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas. 104
Comparative proton NMR studies on bovine semen and pancreas ribonucleases. 104
In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors. 104
The swapping of terminal arms in ribonucleases: comparison of the solution structure of monomeric bovine seminal and pancreatic ribonucleases 103
Binding of human immunoagents and Herceptin to the ErbB2 receptor 103
NOVEL HUMAN ANTI-ErbB2 IMMUNOAGENTS 103
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 102
Strategies for Protein Engineering of Ribonucleases with Farmacological Potentials 102
X-ray diffraction studies of two dimeric variants of human pancreatic ribonuclease 101
Seminal ribonuclease inhibits tumor growth and reduces the metastatic potential of Lewis lung carcinoma. 101
Characterization of the angiogenic activity of zebrafish ribonucleases. 101
Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease 101
Human mini-antibody cytotoxic for tumor cells which express the ErbB2 receptor 100
Selective Deamidation of Ribonuclease A 100
A NEW HUMAN ANTITUMOR IMMUNOREAGENT SPECIFIC FOR ERBB2 99
ESSENTIAL STATIONS IN THE INTRACELLULAR PATHWAYS OF CYTOTOXIC BOVINE SEMINAL RIBONUCLEASE 99
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action. 99
A NEW RNASE BASED IMMUNOCONJUGATE SELECTIVELY CYTOTOXIC FOR ERBB2-OVEREXPRESSING CELLS. 98
RNAases and RISBASES 96
Site-Directed Alkylation and Site-Site Interactions in Bovine Seminal Ribonuclease 96
Anticooperative Binding of Cytidine-2'-Phosphate to Ribonuclease BS-1 96
IL MECCANISMO DATTIVITÀ ANTITUMORALE DELLA RIBONUCLEASI SEMINALE 95
Bull Semen RNAase Revisited 95
The success of the RNase scaffold in the advance of biosciences and in evolution 94
Un nuovo mutante della RNasi A dotato di attività antitumorale 94
DEGRADATION OF DOUBLE-STRANDED RNA BY HUMAN PANCREATIC RIBONUCLEASE: CRUCIAL ROLE OF NONCATALYTIC BASIC AMINO ACID RESIDUES. 93
1H AND 15N SEQUENTIAL ASSIGNEMENT AND SECONDARY STRUCTURE OF THE MONOMERIC N76D MUTANT OF BOVINE SEMINAL RIBONUCLEASE. 93
Temporal and spatial expression of RNases from zebrafish (Danio rerio). 93
A ROLE FOR THE INTERSUBUNIT DISULFIDES OF SEMINAL RNASE IN THE MECHANISM OF ITS ANTITUMOR ACTION. 92
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 92
Seminal RNase: a Unique Member of the Ribonuclease Superfamily 92
Ribonuclease A can be Transformed into a Dimeric Ribonuclease with Antitumor Activity 91
A DIMERIC MUTANT OF HUMAN PANCREATIC RIBONUCLEASE WITH SELECTIVE CYTOTOXICITY TOWARD MALIGNANT CELLS 90
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 90
Thermodynamic stability of five RNases from zebrafish (Danio rerio) 90
LA RIBONUCLEASI PANCREATICA UMANA: INTERAZIONI CON SUBSTRATI ED INIBITORI 87
UN MODELLO SPERIMENTALE PER LO STUDIO DEL RUOLO DELLINIBITORE CITOSOLICO DELLE RIBONUCLEASI 87
Hints on the evolutionary design of a dimeric RNase with special bioactions 87
The Determinants of the Dimeric Structure of Seminal Ribonuclease are Located in its N-Terminal Region 87
Dimeric Organization and Functional Properties of Seminal Ribonuclease: their Relationships with the Structure and Function of Pancreatic RNase 87
THE EVOLUTION OF MONOMERIC AND OLIGOMERIC BETAGAMMA-TYPE CRYSTALLINS. FACTS AND HYPOTHESES. 83
Protein Engineering of RNases of Biological Interest 82
Expression of Bovine Seminal Ribonuclease in Escherichia coli 81
Co-operativity in Seminal Ribonuclease Function: Kinetic Studies 81
Relazioni tra la Struttura Quaternaria della Ribonucleasi BS-1 e la Non Equivalenza Funzionale dei Siti Catalitici 81
Engineering of Seminal RNAase: First Steps Towards the Construction of Chimaeric Ribonucleases 81
Solution structure of the human pancreatic ribonuclease 81
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action 79
From immunotoxins to immunoRNases. 78
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 78
Totale 10.925
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Categoria #
all - tutte 48.664
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.664
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20218 0 0 0 0 0 0 0 0 0 0 0 8
2021/2022950 16 1 4 9 1 36 12 34 202 51 185 399
2022/20231.226 192 109 37 148 139 141 6 116 172 106 45 15
2023/2024657 29 121 81 44 26 46 13 99 3 13 132 50
2024/20253.667 211 194 26 15 108 141 448 206 218 410 1.360 330
2025/20267.030 777 449 682 640 1.387 287 834 465 909 489 102 9
Totale 15.244