IRIS
D'ALESSIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 2.917
EU - Europa 1.368
AS - Asia 960
AF - Africa 33
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 2
OC - Oceania 1
Totale 5.287
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Nazione #
US - Stati Uniti d'America 2.835
SG - Singapore 453
IT - Italia 353
CN - Cina 299
UA - Ucraina 269
IE - Irlanda 191
FI - Finlandia 182
HK - Hong Kong 167
DE - Germania 115
NL - Olanda 106
SE - Svezia 90
CA - Canada 79
GB - Regno Unito 35
CI - Costa d'Avorio 29
IN - India 26
RU - Federazione Russa 10
TR - Turchia 7
EU - Europa 6
FR - Francia 4
VN - Vietnam 4
BE - Belgio 3
AT - Austria 2
IR - Iran 2
LU - Lussemburgo 2
MA - Marocco 2
MX - Messico 2
ZA - Sudafrica 2
AU - Australia 1
BR - Brasile 1
CH - Svizzera 1
CL - Cile 1
EE - Estonia 1
ES - Italia 1
HN - Honduras 1
KR - Corea 1
LK - Sri Lanka 1
LV - Lettonia 1
MK - Macedonia 1
PL - Polonia 1
Totale 5.287
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Città #
Chandler 597
Singapore 373
Jacksonville 275
Millbury 211
Hong Kong 167
Princeton 167
Santa Clara 137
Amsterdam 102
Nanjing 77
Ottawa 76
Wilmington 72
Naples 69
Ashburn 67
Boston 55
Beijing 51
Napoli 43
Woodbridge 39
Houston 37
Cagliari 36
Dearborn 29
Nanchang 27
Kronberg 25
Orange 24
Ann Arbor 23
Falls Church 23
Shenyang 23
Norwalk 21
Boardman 20
Tianjin 18
Seattle 17
Kunming 16
Milan 16
Changsha 15
Pune 14
Helsinki 13
Los Angeles 12
Jiaxing 9
Jinan 9
Bologna 7
Hangzhou 7
Hebei 7
Hyderabad 6
Redmond 6
Washington 6
Dallas 5
Des Moines 5
Guangzhou 5
Indiana 5
Moscow 5
New York 5
Dong Ket 4
Lanzhou 4
Padula 4
Rome 4
Taizhou 4
Zhengzhou 4
Bari 3
Brussels 3
Edinburgh 3
Munich 3
San Francisco 3
San Mateo 3
San Polo 3
Sandston 3
Silopi 3
Springfield 3
Turin 3
Augusta 2
Benevento 2
Bengaluru 2
Cape Town 2
Cava De' Tirreni 2
DeKalb 2
Fisciano 2
Frankfurt am Main 2
Fremont 2
Jinhua 2
Lawrence 2
London 2
Mexico City 2
Mumbai 2
Ningbo 2
Phoenix 2
Redwood City 2
Roccella Jonica 2
Salerno 2
Stillwater 2
Toronto 2
Verona 2
Vienna 2
Walnut 2
Agropoli 1
Albinea 1
Andover 1
Ardabil 1
Avellino 1
Baotou 1
Benxi 1
Birmingham 1
Bolzano 1
Totale 3.188
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Nome #
Ribonucleases and angiogenins from fish. 80
Ribonucleasi Pancreatica e Seminale della Specie Bovina 76
1H and 15N sequential assignment and secondary structure of the monomeric N67D mutant of bovine seminal ribonuclease 74
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish 72
PHYSICO-CHEMICAL CHARACTERZATION OF GEODIN: A NEW B, G- CRYSTALLINE- TYPE PROTEIN SPONGE 64
The success of the RNase scaffold in the advance of biosciences and in evolution 60
3D domain swapping and protein aggregation 58
A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas. 57
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis 56
ON THE THERMAL STABILITY OF THE TWO DIMERIC FORMS OF RIBONUCLEASE A. 56
IL MECCANISMO DATTIVITÀ ANTITUMORALE DELLA RIBONUCLEASI SEMINALE 55
CYTOSOLIC RNASE INHIBITOR ONLY AFFECTS RNASES WITH INTRINSIC CYTOTOXICITY. 55
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 54
A DIMERIC MUTANT OF HUMAN PANCREATIC RIBONUCLEASE WITH SELECTIVE CYTOTOXICITY TOWARD MALIGNANT CELLS 52
LA RIBONUCLEASI PANCREATICA UMANA: INTERAZIONI CON SUBSTRATI ED INIBITORI 51
A NEW HUMAN ANTITUMOR IMMUNOREAGENT SPECIFIC FOR ERBB2 51
ESSENTIAL STATIONS IN THE INTRACELLULAR PATHWAYS OF CYTOTOXIC BOVINE SEMINAL RIBONUCLEASE 51
Anti-ErbB2 human Immunoagents 51
UN MODELLO SPERIMENTALE PER LO STUDIO DEL RUOLO DELLINIBITORE CITOSOLICO DELLE RIBONUCLEASI 50
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action. 50
Combinatorial experimental protocols for Erbicin-derived immunoagents and Herceptin 50
3D domain swapping and supramolecular assembly 50
A dimeric mutant of human pancreas ribonuclease with selective antitumor action 48
A NEW RNASE BASED IMMUNOCONJUGATE SELECTIVELY CYTOTOXIC FOR ERBB2-OVEREXPRESSING CELLS. 47
The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis 47
A novel method for detection of seleno-methionine incorporation in protein crystals via Raman microscopy 47
A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent 47
Immunotoxins and ImmunoRNases 47
Bovine Seminal RNase: an atypical member of the ribonuclease superfamily 46
THE EVOLUTION OF MONOMERIC AND OLIGOMERIC BETAGAMMA-TYPE CRYSTALLINS. FACTS AND HYPOTHESES. 44
1H AND 15N SEQUENTIAL ASSIGNEMENT AND SECONDARY STRUCTURE OF THE MONOMERIC N76D MUTANT OF BOVINE SEMINAL RIBONUCLEASE. 44
The role of electrostatic interactions in the antitumor activity of dimeric RNases 44
Human Antitumor RNases and ImmunoRNases 44
A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours. 44
The molecular basis for the production of an antitumor protein 44
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 43
Effects of a human compact anti-ErbB2 antibody on prostate cancer 43
A new mutein of RNase A with enhanced antitumor action 43
Anticooperative Binding of Cytidine-2'-Phosphate to Ribonuclease BS-1 43
DEGRADATION OF DOUBLE-STRANDED RNA BY HUMAN PANCREATIC RIBONUCLEASE: CRUCIAL ROLE OF NONCATALYTIC BASIC AMINO ACID RESIDUES. 42
Intracellular route and mechanism of action of ERB-hRNase, a human anti-ErbB2 anticancer immunoagent. 42
Mechanisms of cardiotoxicity associated with ErbB2 inhibitors. 42
Bovine seminal ribonuclease, a problem protein 42
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 41
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action 41
The swapping of terminal arms in ribonucleases: comparison of the solution structure of monomeric bovine seminal and pancreatic ribonucleases 41
Muteins of pancreatic ribonuclease and uses thereof 41
Characterization of the angiogenic activity of zebrafish ribonucleases. 41
Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors. 41
A ROLE FOR THE INTERSUBUNIT DISULFIDES OF SEMINAL RNASE IN THE MECHANISM OF ITS ANTITUMOR ACTION. 40
Comparative proton NMR studies on bovine semen and pancreas ribonucleases. 40
Human mini-antibody cytotoxic for tumor cells which express the ErbB2 receptor 39
Anti-ErbB2 immunoagents 39
NUOVI OMOLOGHI DI RIBONUCLEASI E DI BETA,GAMMA-CRISTALLINE DA ORGANISMI MARINI 38
Binding of human immunoagents and Herceptin to the ErbB2 receptor 38
A Novel Human Anti-tumor Dimeric ImmunoRNase 38
Struttura e Funzione della Ribonucleasi BS-1 38
Basi Molecolari dell' Eterogeneità della Ribonucleasi Seminale Bovina 38
Seminal RNAase and Other RISBASES 38
A NEW HUMAN ANTITUMOR IMMUNOREAGENT SPECIFIC FOR ERBB2. 37
Anti-ErbB2 human immunoagents 37
Anti-ErbB2 Human Immunoagents 37
IMMUNORNASES AS ANTITUMOUR AGENTS 37
Ribonucleases with angiogenic and bactericidal activities from the Atlantic salmon 37
Un nuovo mutante della RNasi A dotato di attività antitumorale 37
Seminal ribonuclease: procedures for the preparation of natural and recombinant enzyme, of its quaternary isoforms, of monomeric forms; an assay for the selective cytotoxicity of the enzyme. 36
Temporal and spatial expression of RNases from zebrafish (Danio rerio). 36
Engineering of Seminal RNAase: First Steps Towards the Construction of Chimaeric Ribonucleases 36
Full antitumor action of recombinant seminal ribonuclease depends on the removal of its N-terminal methionine 35
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 34
The bactericidal action on Escherichia coli of ZF-RNase-3 is triggered by the suicidal action of the bacterium OmpT protease. 34
Onconase: an unusually stable mesophilic protein 34
Antitumor Action of Seminal Ribonuclease, Its Dimeric Structure, and Its Resistance to the Cytosolic Ribonuclese Inhibitor 33
Human, Anti-ErbB2 Antitumor Immunoagents 33
Engineering of Bovine Seminal Ribonuclease: Expression of the Secreted Recombinant Protein 33
Antitumor pancreatic-type RNases 33
X-ray diffraction studies of two dimeric variants of human pancreatic ribonuclease 32
The singular case of seminal RNase, a dimer with two quaternary conformations, inspected with Trypsin as a conformational probe 32
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 32
Reattività di-Metà-dei-Siti della Ribonucleasi BS-1 32
Protein engineering of ribonucleases 32
From immunotoxins to immunoRNases. 31
Effects of protein RNase inhibitor and substrate on the quaternary structures of bovine seminal RNase 31
Arginine and Memory Consolidation in Praying Mantis 31
Domain swapping and protein fibril assembly 30
Site-directed mutagenesis induces domain swapping and fibril formation in human pancreatic ribonuclease 30
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 30
Relazioni tra la Struttura Quaternaria della Ribonucleasi BS-1 e la Non Equivalenza Funzionale dei Siti Catalitici 30
Relationships Between Quaternary Structure and S-S Bridges in RNAase BS-1 29
Deammidazione Selettiva della RNAasi BS-1 e suo Ruolo nella Regolazione dell'Attività dell' Enzima 29
Second Generation Antitumour Human RNase: Significance of its Structural and Functional Features for the Mechanism of Antitumour Action 28
Preparation and characterization of geodin. A betagamma-crystallin-type protein from a sponge. 28
NOVEL HUMAN ANTI-ErbB2 IMMUNOAGENTS 28
The Role of Disulfide Bridges in the Dimeric Structure of RNAase BS-1 28
In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors. 27
Investigating site-site interaction of BS-RNase by protein engineering 27
Molecular determinants of the antitumor activity of a ribonuclease 27
Differential binding of human immunoagents and Herceptin to the ErbB2 receptor 27
ESSENTIAL STATIONS IN THE INTRACELLULAR PATHWAYS OF CYTOTOXIC BOVINE SEMINAL RIBONUCLEASE. 26
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin 26
Totale 4.140
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Categoria #
all - tutte 24.893
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.893
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020203 0 0 0 0 0 0 2 2 3 21 76 99
2020/2021508 4 56 57 59 60 78 57 4 56 14 55 8
2021/2022950 16 1 4 9 1 36 12 34 202 51 185 399
2022/20231.226 192 109 37 148 139 141 6 116 172 106 45 15
2023/2024657 29 121 81 44 26 46 13 99 3 13 132 50
2024/2025898 211 194 26 15 108 141 203 0 0 0 0 0
Totale 5.445