IRIS
FRECENTESE, FRANCESCO
 Distribuzione geografica
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Continente #
NA - Nord America 1.465
EU - Europa 1.434
AS - Asia 498
AF - Africa 58
SA - Sud America 13
Continente sconosciuto - Info sul continente non disponibili 3
Totale 3.471
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Nazione #
US - Stati Uniti d'America 1.438
IT - Italia 759
SG - Singapore 282
DE - Germania 215
CN - Cina 166
NL - Olanda 103
FR - Francia 84
IE - Irlanda 73
FI - Finlandia 55
CI - Costa d'Avorio 53
UA - Ucraina 33
GB - Regno Unito 32
CA - Canada 27
VN - Vietnam 20
SE - Svezia 17
ES - Italia 14
BR - Brasile 12
IN - India 11
BG - Bulgaria 10
PL - Polonia 10
GR - Grecia 9
JP - Giappone 9
AT - Austria 6
SK - Slovacchia (Repubblica Slovacca) 4
CH - Svizzera 3
EG - Egitto 3
EU - Europa 3
TR - Turchia 3
HK - Hong Kong 2
IR - Iran 2
SI - Slovenia 2
BE - Belgio 1
CL - Cile 1
CZ - Repubblica Ceca 1
KG - Kirghizistan 1
MA - Marocco 1
NO - Norvegia 1
PH - Filippine 1
PK - Pakistan 1
RS - Serbia 1
RU - Federazione Russa 1
TN - Tunisia 1
Totale 3.471
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Città #
Chandler 280
Singapore 238
Naples 187
Amsterdam 94
Napoli 84
Millbury 79
Menlo Park 76
Krefeld 46
Beijing 45
Nanjing 45
Santa Clara 45
Princeton 44
Jacksonville 41
Des Moines 37
Boston 32
Ashburn 30
Woodbridge 28
Ottawa 26
Lawrence 25
Bad Bellingen 24
Wilmington 23
Dong Ket 20
Pozzuoli 20
San Giorgio a Cremano 17
Redwood City 16
Houston 15
Rome 15
Milan 14
Nanchang 14
Dearborn 11
Mugnano di Napoli 11
Cambridge 10
Hebei 10
Salerno 10
Athens 9
Sofia 9
Trieste 9
Jiaxing 8
Dallas 7
Roccarainola 7
Scunthorpe 7
Zola Predosa 7
Dublin 6
Ercolano 6
Falcone 6
Helsinki 6
Indiana 6
Jena 6
Krakow 6
Norwalk 6
Changsha 5
Council Bluffs 5
Lappeenranta 5
Vienna 5
Barano d'Ischia 4
Boardman 4
Bratislava 4
Caserta 4
Casoria 4
Fucecchio 4
Pisa 4
Santiago De Compostela 4
Shenyang 4
Shenzhen 4
Afragola 3
Ann Arbor 3
Aversa 3
Bacoli 3
Doshin 3
Fairfield 3
Giugliano in Campania 3
Kronberg 3
Kunming 3
Livorno 3
Los Angeles 3
Lucca 3
Marigliano 3
Padenghe sul Garda 3
Pomigliano d'Arco 3
Pune 3
Rho 3
San Francisco 3
Secunderabad 3
Serino 3
Serra 3
Tarragona 3
Tianjin 3
Valdagno 3
Vallo della Lucania 3
Verona 3
Ardabil 2
Avellino 2
Bologna 2
Castel Volturno 2
Centro 2
Chofu 2
Crispano 2
Eindhoven 2
Falls Church 2
Formia 2
Totale 1.981
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Nome #
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 203
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 182
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 102
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 84
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 79
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 74
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 74
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 69
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 68
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 65
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 64
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 60
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 58
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 57
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 56
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 55
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 54
A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation 54
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 54
A valuable synthesis of reduced peptide bond by microwave irradiation 52
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 51
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 50
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 49
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 48
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 48
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 48
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 48
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 46
Identification of a pepducin acting as S1P3 receptor antagonist 46
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 46
Montelukast salts and pharmaceutical compositions containing the same 46
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 44
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 43
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 43
Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-​1 nucleocapsid inhibitors 42
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 40
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 40
Lipophilic and polar interaction forces between acidic drugs and membrane phospholipids encoded in IAM-HPLC indexes: their role in membrane partition and relationships with BBB permeation data. 39
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 39
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 38
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 38
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 38
Novel tools for the elucidation of physio-pathological role of H2S 36
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 36
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 35
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands 35
Quantification of dapaconazole in human plasma using high-​performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study 35
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 35
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 34
Design and synthesis of potential b-sheet nucleatorsvia Suzuki coupling reaction 34
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 34
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 34
Synthesis of benzamide derivatives and their evaluation as antiprion agents 33
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 31
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 31
Racemic synthesis and solid phase peptide synthesis application of the chimeric Valine/Leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid 30
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 30
Inhibition of rat vas deferens contractions by flavonoids in-vitro 29
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 29
The application of microwaves in combinatorial and high-throughput synthesis as new synthetic procedure in drug discovery. 29
H2s donors and their use in medicinal chemistry 29
Synthesis and in vitro pharmacological evaluation of a new series of 5-HT1A 5-HT2A and 5-HT2C receptor ligands containing a norbornene nucleus. 28
Involvement of 3′,5′-cyclic inosine monophosphate in cystathionine γ-lyase-dependent regulation of the vascular tone 28
Efficient microwave-assisted synthesis of 4-amino-2-benzazepin-3-ones as conformationally restricted dipeptide mimetics 25
New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: Synthesis and in vitro pharmacological evaluation 25
Propylthiouracil quantification in human plasma by high-​performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study 25
Synthesis and pharmacological evaluation of peptide-mimetic protease-activated receptor-1 antagonists containing novel heterocyclic scaffolds 24
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 24
Multiple in Vitro Inhibition of HIV-1 Proteins by 2,6-Dipeptidyl-anthraquinone Conjugates Targeting the PBS RNA 23
The Application of Microwaves, Ultrasounds, and Their Combination in the Synthesis of Nitrogen-Containing Bicyclic Heterocycles 22
Synthesis by microwave irradiation and antidiarrhoeal activity of benzotriazinone and saccharine derivatives. 22
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 22
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 21
Microwave Assisted Synthesis: A New Technology in Drug Discovery 21
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 20
Synthesis and in-vitro pharmacological evaluation of new 5-HT1A receptor ligands containing a benzotriazinone nucleus 20
Recent Advances in Synthesis of PAR Ligands as Therapeutic Strategy for Inflammatory Diseases 20
Process for the preparation of budesonide 21-phosphate 19
Synthesis and Pharmacological Evaluations of Sildenafil Analogues for Treatment of Erectile Dysfunction. 17
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 16
Technological and Physical–Chemical Evaluation of Cotton Gauzes Impregnated with Semisolid Preparations for Wound Healing 16
Measurement of 6‐cyanodopamine, 6‐nitrodopa, 6‐nitrodopamine and 6‐nitroadrenaline by LC–MS/MS in Krebs–Henseleit solution. Assessment of basal release from rabbit isolated right atrium and ventricles 13
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 13
Quantification of estradiol cypionate in plasma by liquid chromatography coupled with tandem mass spectrometry: Application in a pharmacokinetic study in healthy female volunteers 13
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 10
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 10
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 10
Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties 9
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 4
GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens 2
Totale 3.675
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Categoria #
all - tutte 15.874
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.874
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020228 0 0 0 0 52 31 23 11 12 27 43 29
2020/2021209 15 12 9 7 26 20 27 5 19 8 24 37
2021/2022656 3 3 5 146 16 28 2 25 63 60 129 176
2022/2023706 84 92 18 54 61 67 15 56 101 90 47 21
2023/2024736 24 83 114 21 17 18 41 65 205 18 84 46
2024/2025473 128 168 40 66 71 0 0 0 0 0 0 0
Totale 3.675