IRIS
VIRGILIO, ANTONELLA
 Distribuzione geografica
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Continente #
AS - Asia 3.917
NA - Nord America 3.565
EU - Europa 3.104
SA - Sud America 479
AF - Africa 97
OC - Oceania 10
Totale 11.172
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Nazione #
US - Stati Uniti d'America 3.440
SG - Singapore 1.720
RU - Federazione Russa 1.168
IT - Italia 969
VN - Vietnam 738
CN - Cina 737
BR - Brasile 389
HK - Hong Kong 279
DE - Germania 164
FR - Francia 137
FI - Finlandia 120
NL - Olanda 113
UA - Ucraina 88
IN - India 84
JP - Giappone 84
IE - Irlanda 83
GB - Regno Unito 70
SE - Svezia 70
CA - Canada 60
MX - Messico 38
ZA - Sudafrica 36
AR - Argentina 31
PL - Polonia 31
BD - Bangladesh 28
PH - Filippine 25
CI - Costa d'Avorio 23
IQ - Iraq 23
KR - Corea 23
TR - Turchia 21
ID - Indonesia 20
PT - Portogallo 19
TH - Thailandia 19
PK - Pakistan 17
EC - Ecuador 14
ES - Italia 12
CL - Cile 11
AU - Australia 10
TW - Taiwan 10
AT - Austria 9
CO - Colombia 9
MA - Marocco 9
PY - Paraguay 9
UZ - Uzbekistan 9
VE - Venezuela 9
BE - Belgio 8
IR - Iran 8
AE - Emirati Arabi Uniti 7
AZ - Azerbaigian 7
IL - Israele 7
AM - Armenia 6
KZ - Kazakistan 6
SA - Arabia Saudita 6
CZ - Repubblica Ceca 5
JM - Giamaica 5
KE - Kenya 5
RO - Romania 5
CR - Costa Rica 4
JO - Giordania 4
MY - Malesia 4
NP - Nepal 4
PE - Perù 4
TN - Tunisia 4
BB - Barbados 3
DZ - Algeria 3
HU - Ungheria 3
KG - Kirghizistan 3
KH - Cambogia 3
LT - Lituania 3
SD - Sudan 3
SI - Slovenia 3
SK - Slovacchia (Repubblica Slovacca) 3
YE - Yemen 3
BH - Bahrain 2
BY - Bielorussia 2
DO - Repubblica Dominicana 2
EE - Estonia 2
EG - Egitto 2
GR - Grecia 2
HN - Honduras 2
HR - Croazia 2
MD - Moldavia 2
MK - Macedonia 2
MN - Mongolia 2
MT - Malta 2
MU - Mauritius 2
NI - Nicaragua 2
OM - Oman 2
PA - Panama 2
SN - Senegal 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BG - Bulgaria 1
CD - Congo 1
CH - Svizzera 1
Totale 11.155
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Città #
Singapore 844
San Jose 541
Chandler 476
Moscow 278
Ashburn 269
Hong Kong 268
Naples 263
Beijing 235
Napoli 190
Ho Chi Minh City 175
Hanoi 144
Santa Clara 136
Amsterdam 96
The Dalles 95
Lauterbourg 85
Los Angeles 83
Millbury 82
Jacksonville 80
Dong Ket 78
Princeton 72
Nanjing 70
Hefei 68
Boston 61
Tokyo 54
Council Bluffs 46
New York 40
Buffalo 38
Wilmington 37
Da Nang 34
São Paulo 34
Des Moines 33
Haiphong 33
Munich 32
Redondo Beach 32
Orem 27
Seattle 26
Portici 25
Ann Arbor 23
Helsinki 22
Houston 22
Nanchang 21
Turku 21
Brooklyn 20
Rome 20
Dallas 19
Ottawa 19
Denver 17
Frankfurt am Main 17
Hangzhou 16
Milan 16
Warsaw 16
Biên Hòa 15
Hebei 15
Lawrence 15
Shenyang 15
Phoenix 14
Rio de Janeiro 14
Augusta 13
Boardman 13
Chennai 13
Dearborn 13
Mexico City 13
Montreal 13
Mumbai 13
Paris 13
Toronto 13
Baghdad 12
Falls Church 12
Formia 12
Jiaxing 12
Johannesburg 12
Caserta 11
Changsha 11
Chicago 11
Falkenstein 11
Marano Di Napoli 11
Poznan 11
Tianjin 11
Brasília 10
Kronberg 10
London 10
Salerno 10
Washington 10
Bangkok 9
Guangzhou 9
Lappeenranta 9
Manchester 9
Nuremberg 9
Pune 9
San Francisco 9
Belo Horizonte 8
Brisbane 8
Campinas 8
Can Tho 8
Dublin 8
Kharagpur 8
Kochi 8
Lisbon 8
Nocera Inferiore 8
Poplar 8
Totale 5.984
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Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 214
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 179
A New Modified Thrombin Binding Aptamer Containing a 5'-5' Inversion of Polarity site 169
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 161
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 160
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 160
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 151
MOLECULAR MODELLING STUDIES OF A PARALLEL STRANDED QUADRUPLEX CONTAING A 8-BROMOADENO 149
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 146
Backbone modified TBA analogues endowed with antiproliferative activity 146
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 146
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 145
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 143
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 143
A topological classification of G-quadruplex structures 141
Quadruplex DNA: structural features and potential applications 141
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 141
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 139
Structural studies and biological evaluation of T30695 variants modified with single chiral glycerol-T reveal the importance of LEDGF/p75 for the aptamer anti-HIV-integrase activities 139
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 138
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 137
Heterochiral oligodeoxynucleotides forming quadruplex structures 136
Effects of a 8-oxoadenosine Incorporation on Quadruplex structures: thermal stabilities and structural studies 134
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 133
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 132
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 131
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 130
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 129
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 128
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 128
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 127
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 127
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 126
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 125
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 125
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 125
Heterochiral oligodeoxynucleotides forming quadruplex structures 125
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 125
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 125
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 122
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 120
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 119
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 119
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 119
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 118
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 118
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 118
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 117
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 117
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 117
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 117
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 117
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 117
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 116
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 116
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 112
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 108
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 108
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 108
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 107
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 107
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 107
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 106
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 105
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 105
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 105
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 105
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 104
Investigating the properties of TBA variants with twin thrombin binding domains 104
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 104
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 103
NMR Structure of the Complex between Distamycin A and the Four Stranded Quadruplex Structure [d(TGGGGT)]4 102
STUDIES ON HETEROCHIRAL OLIGONUCLEOTIDES FORMING QUADRUPLEX STRUCTURES 102
Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides 102
Structural Studies on LNA Quadruplexes 100
Structural Investigations on the Anti-HIV G-Quadruplex-Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A-Tetrad 100
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 100
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 99
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 99
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 93
GLI EFFETTI DELL'INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA' SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 90
Molecular modeling studies of a parallel stranded quadruplexes containing a 8-bromoadenosine 89
Formulazione costituita da snalp contenente pre-mir 34a utile per il trattamento del mieloma multiplo 88
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 88
Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide Gquadruplexes with double 3′-external G-quartets 88
Interaction of Distamycin A and its Derivatives with DNA QuadruplexStructures 86
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 86
Trisubstituted naphthalimides for DNA quadruplex binding selectivity: synthesis, NMR and biophysical studies 85
Effects of 5-Methyl-2′-Deoxycytidine in G-Quadruplex Forming Aptamers d(G3C)4 and d[GCG2(CG3)3C]: Investigating the Key Role of the Loops 78
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence 77
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 70
Studies on the influence of inversion of polarity sites on the dG residues glycosidic conformation in quadruplex structures 69
Effects of the introduction of the inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT. 68
Novel monomolecular derivatives of the anti-HIV-1 G-quadruplex-forming Hotoda's aptamer containing inversion of polarity sites 67
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma 64
A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site 62
Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes 61
Probing the importance of the G-quadruplex grooves for the activity of the anti-HIV-integrase aptamer T30923 60
More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures 59
Impact of Thymidine Loop Modifications on Telomeric G-Quadruplex Catalytic Systems for Asymmetric Sulfoxidation 36
Totale 11.452
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Categoria #
all - tutte 33.922
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.922
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021125 0 0 0 0 0 0 0 0 0 0 41 84
2021/2022593 11 0 5 13 11 45 4 31 87 76 99 211
2022/20231.044 120 78 30 148 85 144 5 118 145 102 58 11
2023/2024493 18 87 39 30 31 50 19 95 9 7 76 32
2024/20252.603 124 130 8 13 134 128 315 174 162 252 963 200
2025/20265.218 491 427 575 456 987 183 570 367 656 372 134 0
Totale 11.490