IRIS
VIRGILIO, ANTONELLA
 Distribuzione geografica
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Continente #
NA - Nord America 1.836
EU - Europa 1.251
AS - Asia 614
AF - Africa 28
OC - Oceania 10
SA - Sud America 8
Totale 3.747
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Nazione #
US - Stati Uniti d'America 1.809
IT - Italia 714
SG - Singapore 243
CN - Cina 215
NL - Olanda 91
IE - Irlanda 79
VN - Vietnam 79
UA - Ucraina 77
FI - Finlandia 70
DE - Germania 62
SE - Svezia 61
GB - Regno Unito 25
IN - India 25
CA - Canada 24
CI - Costa d'Avorio 23
JP - Giappone 22
FR - Francia 19
PL - Polonia 13
AU - Australia 10
HK - Hong Kong 8
TR - Turchia 8
PT - Portogallo 7
CL - Cile 6
CZ - Repubblica Ceca 5
IR - Iran 5
BE - Belgio 4
RU - Federazione Russa 4
AM - Armenia 3
ES - Italia 3
SD - Sudan 3
TW - Taiwan 3
AT - Austria 2
CR - Costa Rica 2
HU - Ungheria 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
AL - Albania 1
BG - Bulgaria 1
CH - Svizzera 1
CO - Colombia 1
EE - Estonia 1
HR - Croazia 1
KR - Corea 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PK - Pakistan 1
PR - Porto Rico 1
PY - Paraguay 1
RO - Romania 1
ZA - Sudafrica 1
Totale 3.747
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Città #
Chandler 476
Singapore 201
Napoli 190
Naples 134
Ashburn 112
Amsterdam 88
Millbury 82
Dong Ket 78
Jacksonville 78
Princeton 72
Nanjing 68
Santa Clara 61
Boston 48
Wilmington 37
Des Moines 33
Beijing 32
Ann Arbor 23
Nanchang 21
Ottawa 18
Hangzhou 15
Hebei 15
Lawrence 15
Boardman 13
Dearborn 13
Houston 13
Augusta 12
Falls Church 12
Formia 12
Jiaxing 12
Shenyang 12
Caserta 11
Marano Di Napoli 11
Poznan 11
Kronberg 10
Washington 10
Paris 9
Brisbane 8
Changsha 8
Hong Kong 8
Milan 8
Nocera Inferiore 8
Redwood City 8
Rome 8
Seattle 8
Norwalk 7
Pune 7
Salerno 7
Tianjin 6
Dublin 5
Edinburgh 5
Giugliano in Campania 5
Guangzhou 5
Portici 5
Brno 4
Hyderabad 4
Kharagpur 4
Los Angeles 4
New York 4
Roccarainola 4
San Francisco 4
San Giorgio A Cremano 4
Simi Valley 4
Bologna 3
Braga 3
Brussels 3
Cambridge 3
Grumo Nevano 3
Kanazawa 3
Padula 3
Piana 3
Pomigliano D'arco 3
Pomigliano d'Arco 3
Rohtak 3
San Giorgio 3
San Mateo 3
Torre Del Greco 3
Turin 3
Woodbridge 3
Yerevan 3
Acerra 2
Arzano 2
Aszod 2
Bari 2
Brampton 2
Capri 2
Castello di Cisterna 2
Chatham 2
Crane Hill 2
Crispano 2
Curti 2
Fairfield 2
Gainesville 2
Genova 2
Gragnano 2
Groningen 2
Kish 2
Kunming 2
L'aquila 2
La Serena 2
Lappeenranta 2
Totale 2.303
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Nome #
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 91
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 89
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 89
Backbone modified TBA analogues endowed with antiproliferative activity 86
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 75
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 73
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 70
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 70
MOLECULAR MODELLING STUDIES OF A PARALLEL STRANDED QUADRUPLEX CONTAING A 8-BROMOADENO 68
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 65
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 63
A New Modified Thrombin Binding Aptamer Containing a 5'-5' Inversion of Polarity site 63
Structural studies and biological evaluation of T30695 variants modified with single chiral glycerol-T reveal the importance of LEDGF/p75 for the aptamer anti-HIV-integrase activities 61
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 60
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 60
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 60
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 60
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 60
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 59
A topological classification of G-quadruplex structures 57
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 56
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 56
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 56
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 56
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 54
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 54
Quadruplex DNA: structural features and potential applications 53
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 52
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 52
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 52
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 51
Effects of a 8-oxoadenosine Incorporation on Quadruplex structures: thermal stabilities and structural studies 49
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 48
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 48
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 47
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 46
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 44
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 44
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 44
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 44
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 44
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 44
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 43
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 43
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 43
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 43
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 43
Molecular modeling studies of a parallel stranded quadruplexes containing a 8-bromoadenosine 42
Investigating the properties of TBA variants with twin thrombin binding domains 42
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 41
Structural Studies on LNA Quadruplexes 40
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 40
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 39
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 39
Trisubstituted naphthalimides for DNA quadruplex binding selectivity: synthesis, NMR and biophysical studies 39
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 39
Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide Gquadruplexes with double 3′-external G-quartets 37
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 36
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 35
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 35
Heterochiral oligodeoxynucleotides forming quadruplex structures 35
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 34
Heterochiral oligodeoxynucleotides forming quadruplex structures 34
Formulazione costituita da snalp contenente pre-mir 34a utile per il trattamento del mieloma multiplo 34
Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides 34
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 34
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 33
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 31
Structural Investigations on the Anti-HIV G-Quadruplex-Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A-Tetrad 31
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 31
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 31
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 31
STUDIES ON HETEROCHIRAL OLIGONUCLEOTIDES FORMING QUADRUPLEX STRUCTURES 30
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 29
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence 28
NMR Structure of the Complex between Distamycin A and the Four Stranded Quadruplex Structure [d(TGGGGT)]4 25
A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site 25
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma 25
Studies on the influence of inversion of polarity sites on the dG residues glycosidic conformation in quadruplex structures 24
Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes 22
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 22
More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures 20
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 20
Novel monomolecular derivatives of the anti-HIV-1 G-quadruplex-forming Hotoda's aptamer containing inversion of polarity sites 20
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 20
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 20
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 19
Effects of the introduction of the inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT. 17
Interaction of Distamycin A and its Derivatives with DNA QuadruplexStructures 17
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 16
Probing the importance of the G-quadruplex grooves for the activity of the anti-HIV-integrase aptamer T30923 16
null 10
GLI EFFETTI DELL'INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA' SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 9
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 8
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 7
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 6
null 6
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 4
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 4
Totale 4.054
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Categoria #
all - tutte 15.658
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.658
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020191 0 0 0 0 50 12 30 3 14 11 35 36
2020/2021477 12 18 32 17 63 60 30 24 90 6 41 84
2021/2022593 11 0 5 13 11 45 4 31 87 76 99 211
2022/20231.044 120 78 30 148 85 144 5 118 145 102 58 11
2023/2024493 18 87 39 30 31 50 19 95 9 7 76 32
2024/2025385 124 130 8 13 110 0 0 0 0 0 0 0
Totale 4.054