Five fragments, 2a-4b, embedding all the stereogenic centers of reidispongiolide A (1), have been prepared by a controlled ozonolysis of the natural compound. The absolute stereochemistry of the asymmetric centers of fragment 3, corresponding to the C17-C22 portion of reidispongiolide A, was determined by enantioselective synthesis and application of the advanced Mosher method.
Stereochemistry of Sphinxolides and Reidispongiolides. Asymmetric Synthesis of C17-C22 fragment of reidispongiolide A / Zampella, Angela; Bassarello, C.; Bifulco, G.; Gomez Paloma, L.; D'Auria, MARIA VALERIA. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - STAMPA. - 5(2002), pp. 785-790. [10.1002/1099-0690(200203)2002:5]
Stereochemistry of Sphinxolides and Reidispongiolides. Asymmetric Synthesis of C17-C22 fragment of reidispongiolide A
ZAMPELLA, ANGELA;D'AURIA, MARIA VALERIA
2002
Abstract
Five fragments, 2a-4b, embedding all the stereogenic centers of reidispongiolide A (1), have been prepared by a controlled ozonolysis of the natural compound. The absolute stereochemistry of the asymmetric centers of fragment 3, corresponding to the C17-C22 portion of reidispongiolide A, was determined by enantioselective synthesis and application of the advanced Mosher method.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
