The photocatalytic degradation of an antibiotic, vancomycin B hydrochloride (VAN-B), has been investigated in aqueous suspensions of titanium dioxide (TiO2) by monitoring the change in its concentration as well as the production of ammonia and chlorides as a function of irradiation time. The removal of 50 mg L-1 VAN-B solution yields maximum concentrations of 2.45 and 2.53 mg N-NH3 L-1 after 120 min of photocatalytic oxidation using 0.1 and 0.2 g TiO2 L-1, respectively. When 0.2 g TiO2 L-1 were applied up to 87% of the stoichiometric amount of chloride was reached within 120 min of irradiation, corresponding to 0.087 mmol L-1.A set of bioassays (Daphnia magna, Pseudokirchneriella subcapitata and Ceriodaphnia dubia) was performed to evaluate the potential detoxification of VAN-B and its by-products of oxidation under chronic and acute tests. The toxicity of the treated VAN-B samples varied during the oxidation, due to the formation of some intermediate products more toxic than VAN-B. Despite almost total removal of VAN-B that was achieved within 120 min of irradiation, a significant increase in toxicity was observed in chronic tests proving that the chronic assays are more appropriate than acute ones to detect the impact of by-products formed during the photocatalytic degradation of
An integrated chemical and ecotoxicological assessment for the photocatalytic degradation of vancomycin / Lofrano, G.; Carotenuto, M.; Uyguner Demirel, C. S.; Vitagliano, A.; Siciliano, A.; Guida, Marco. - In: ENVIRONMENTAL TECHNOLOGY. - ISSN 0959-3330. - 35:10(2014), pp. 1234-1242. [10.1080/09593330.2013.865085]
An integrated chemical and ecotoxicological assessment for the photocatalytic degradation of vancomycin
Lofrano G.;Siciliano A.;GUIDA, MARCO
2014
Abstract
The photocatalytic degradation of an antibiotic, vancomycin B hydrochloride (VAN-B), has been investigated in aqueous suspensions of titanium dioxide (TiO2) by monitoring the change in its concentration as well as the production of ammonia and chlorides as a function of irradiation time. The removal of 50 mg L-1 VAN-B solution yields maximum concentrations of 2.45 and 2.53 mg N-NH3 L-1 after 120 min of photocatalytic oxidation using 0.1 and 0.2 g TiO2 L-1, respectively. When 0.2 g TiO2 L-1 were applied up to 87% of the stoichiometric amount of chloride was reached within 120 min of irradiation, corresponding to 0.087 mmol L-1.A set of bioassays (Daphnia magna, Pseudokirchneriella subcapitata and Ceriodaphnia dubia) was performed to evaluate the potential detoxification of VAN-B and its by-products of oxidation under chronic and acute tests. The toxicity of the treated VAN-B samples varied during the oxidation, due to the formation of some intermediate products more toxic than VAN-B. Despite almost total removal of VAN-B that was achieved within 120 min of irradiation, a significant increase in toxicity was observed in chronic tests proving that the chronic assays are more appropriate than acute ones to detect the impact of by-products formed during the photocatalytic degradation ofI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.