Protein digestomics: Integrated platforms to study food-protein digestion and derived functional and active peptides

In the global perspective of ‘‘foodomics’’, tracking the fate of food proteins upon gastrointestinal (GI) digestion assumes a particular relevance, because the products of protein degradation comprise possible functional components with positive (health-promoting activity) or adverse (allergy, intolerance, toxicity) effects on human health. Here we review the recent contributions of the ‘omic’ sciences to characterize the protein ‘‘digestomes’’ and, in perspective, to validate the experimental models of digestion, with the ultimate scope of elucidating the kinetics and dynamics of dietary proteins.