Beta-adrenergic vasodilation plays a key role in the regulation of coronary blood flow, in particular during sympathetic nervous system activation. Beta1-adrenergic receptors are mostly represented in epicardial coronary vessel, while β2 receptors are located in microvasculature. Coronary atherosclerosis is associated with a significant impairment of β-adrenergic receptor response. This might contribute to precipitate myocardial ischemia.
Current concepts and clinical applications of coronary beta adrenergic receptors [Attuali concetti sulla fisiopatologia dei recettori beta-adrenergici nelle coronarie e sulle sue applicazioni cliniche] / Barbato, Emanuele; Wijns, W; De Bruyne, B; Mascia, G; Piscione, F.. - In: RECENTI PROGRESSI IN MEDICINA. - ISSN 0034-1193. - 96:9(2005), pp. 411-415.
Current concepts and clinical applications of coronary beta adrenergic receptors [Attuali concetti sulla fisiopatologia dei recettori beta-adrenergici nelle coronarie e sulle sue applicazioni cliniche]
BARBATO, EMANUELE;
2005
Abstract
Beta-adrenergic vasodilation plays a key role in the regulation of coronary blood flow, in particular during sympathetic nervous system activation. Beta1-adrenergic receptors are mostly represented in epicardial coronary vessel, while β2 receptors are located in microvasculature. Coronary atherosclerosis is associated with a significant impairment of β-adrenergic receptor response. This might contribute to precipitate myocardial ischemia.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
