Background: The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life (QoL) of affected patients; however, the problem remains under-recognized and under-treated. We conducted an Italian consensus through a modified Delphi survey to discuss the current treatment paradigm of drooling in pediatric patients with neurological disorders. Methods: After reviewing the literature, a board of 10 experts defined some statements to be administered to a multidisciplinary panel through an online encrypted platform. The answers to the questions were based on a 1-5 Likert scale (1 = strongly disagree; 5 = strongly agree). The scores were grouped into 1-2 (disagreement) and 4-5 (agreement), while 3 was discarded. The consensus was reached when the sum of the disagreement or agreement was ≥75%. Results: Fifteen statements covered three main topics, namely clinical manifestations and QoL, quantification of drooling, and treatment strategies. All statements reached consensus (≥75% agreement). The 55 Italian experts agreed that drooling should be assessed in all children with complex needs, having a major impact on the QoL. Attention should be paid to investigating posterior hypersalivation, which is often neglected but may lead to important clinical consequences. Given that the severity of drooling fluctuates over time, its management should be guided by the patients' current needs. Furthermore, the relative lack of validated and universal scales for drooling quantification limits the evaluation of the response to treatment. Finally, the shared therapeutic paradigm is progressive, with conservative treatments preceding the pharmacological ones and reserving surgery only for selected cases. Conclusion: This study demonstrates the pivotal importance of a multidisciplinary approach to the management of drooling. National experts agree that progressive treatment can reduce the incidence of complications, improve the QoL of patients and caregivers, and save healthcare resources. Finally, this study highlights how the therapeutic strategy should be reconsidered over time according to the available drugs on the market, the progression of symptoms, and the patients' needs.
Impact and management of drooling in children with neurological disorders: an Italian Delphi consensus / Riva, A.; Amadori, E.; Vari, M. S.; Spalice, A.; Belcastro, V.; Viri, M.; Capodiferro, D.; Romeo, A.; Verrotti, A.; Aiello, M. F.; Bagnasco, I.; Battistella, P. A.; Bergamoni, S.; Boldrini, B.; Bratta, P.; Brusaferro, A.; Brusco, M.; Burchiani, B.; Burdino, E.; Cardinali, B.; Cassani, M.; Cavalli, E.; Cavallini, A.; Duccio, M. C.; D'Agata, G.; Di Corcia, G.; D'Onofrio, G.; Fagiolari, G.; Fattorusso, A.; Felicioni, M.; Gaiotti, F.; Galati, C.; Gasola, L.; Giaquinto, G.; Gizzi, C.; Grasso, D. L.; Isidori, C.; Marcucci, M. T.; Mazzoni, V.; Mencaroni, E.; Monacelli, G.; Nicita, F.; Orsini, A.; Pellegrino, A.; Peruzzi, C.; Piccolo, G.; Pistola, I.; Prezioso, G.; Pulitano, P.; Raieli, V.; Saladino, M.; Sapuppo, A.; Sica, R.; Spagnoli, C.; Tagliente, M.; Tascini, G.; Terrone, G.; Tulli, E.; Vinti, V.; Striano, P.. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1824-7288. - 48:1(2022). [10.1186/s13052-022-01312-8]
Impact and management of drooling in children with neurological disorders: an Italian Delphi consensus
Riva A.;Vari M. S.;Cavallini A.;Pistola I.;Terrone G.;Striano P.
2022
Abstract
Background: The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life (QoL) of affected patients; however, the problem remains under-recognized and under-treated. We conducted an Italian consensus through a modified Delphi survey to discuss the current treatment paradigm of drooling in pediatric patients with neurological disorders. Methods: After reviewing the literature, a board of 10 experts defined some statements to be administered to a multidisciplinary panel through an online encrypted platform. The answers to the questions were based on a 1-5 Likert scale (1 = strongly disagree; 5 = strongly agree). The scores were grouped into 1-2 (disagreement) and 4-5 (agreement), while 3 was discarded. The consensus was reached when the sum of the disagreement or agreement was ≥75%. Results: Fifteen statements covered three main topics, namely clinical manifestations and QoL, quantification of drooling, and treatment strategies. All statements reached consensus (≥75% agreement). The 55 Italian experts agreed that drooling should be assessed in all children with complex needs, having a major impact on the QoL. Attention should be paid to investigating posterior hypersalivation, which is often neglected but may lead to important clinical consequences. Given that the severity of drooling fluctuates over time, its management should be guided by the patients' current needs. Furthermore, the relative lack of validated and universal scales for drooling quantification limits the evaluation of the response to treatment. Finally, the shared therapeutic paradigm is progressive, with conservative treatments preceding the pharmacological ones and reserving surgery only for selected cases. Conclusion: This study demonstrates the pivotal importance of a multidisciplinary approach to the management of drooling. National experts agree that progressive treatment can reduce the incidence of complications, improve the QoL of patients and caregivers, and save healthcare resources. Finally, this study highlights how the therapeutic strategy should be reconsidered over time according to the available drugs on the market, the progression of symptoms, and the patients' needs.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
