IRIS
PIGNATARO, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 6.146
NA - Nord America 5.210
EU - Europa 5.087
SA - Sud America 713
AF - Africa 142
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 4
Totale 17.307
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Nazione #
US - Stati Uniti d'America 5.005
SG - Singapore 2.726
RU - Federazione Russa 2.036
IT - Italia 1.415
VN - Vietnam 1.201
CN - Cina 1.197
BR - Brasile 575
HK - Hong Kong 454
DE - Germania 355
FR - Francia 240
NL - Olanda 225
FI - Finlandia 215
GB - Regno Unito 148
UA - Ucraina 134
CA - Canada 123
IE - Irlanda 93
JP - Giappone 89
IN - India 87
SE - Svezia 69
AR - Argentina 57
MX - Messico 51
BD - Bangladesh 49
CI - Costa d'Avorio 48
KR - Corea 47
TR - Turchia 42
PL - Polonia 41
IQ - Iraq 32
ZA - Sudafrica 32
ES - Italia 26
ID - Indonesia 26
TH - Thailandia 26
EC - Ecuador 24
PH - Filippine 23
AT - Austria 22
JO - Giordania 17
PK - Pakistan 17
TW - Taiwan 15
SA - Arabia Saudita 13
KE - Kenya 12
PY - Paraguay 11
UZ - Uzbekistan 10
VE - Venezuela 10
CL - Cile 9
BE - Belgio 8
CO - Colombia 8
LT - Lituania 8
NP - Nepal 8
AZ - Azerbaigian 7
IL - Israele 7
LB - Libano 7
MA - Marocco 7
TN - Tunisia 7
BG - Bulgaria 6
CH - Svizzera 6
EG - Egitto 6
HR - Croazia 6
PE - Perù 6
BO - Bolivia 5
CZ - Repubblica Ceca 5
NG - Nigeria 5
OM - Oman 5
AE - Emirati Arabi Uniti 4
AU - Australia 4
GA - Gabon 4
HU - Ungheria 4
SV - El Salvador 4
TJ - Tagikistan 4
UY - Uruguay 4
AL - Albania 3
CY - Cipro 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
ET - Etiopia 3
GR - Grecia 3
IR - Iran 3
JM - Giamaica 3
KG - Kirghizistan 3
KH - Cambogia 3
KW - Kuwait 3
MY - Malesia 3
PT - Portogallo 3
SR - Suriname 3
ZM - Zambia 3
BH - Bahrain 2
CR - Costa Rica 2
CW - ???statistics.table.value.countryCode.CW??? 2
GD - Grenada 2
GE - Georgia 2
GP - Guadalupe 2
GT - Guatemala 2
KZ - Kazakistan 2
LC - Santa Lucia 2
LK - Sri Lanka 2
LV - Lettonia 2
MK - Macedonia 2
NA - Namibia 2
NI - Nicaragua 2
SI - Slovenia 2
SN - Senegal 2
Totale 17.272
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Città #
Singapore 1.345
San Jose 795
Ashburn 692
Moscow 491
Chandler 485
Hong Kong 437
Naples 433
Beijing 378
Ho Chi Minh City 354
Hanoi 266
Amsterdam 191
Santa Clara 168
Napoli 167
Hefei 166
Los Angeles 153
Lauterbourg 137
The Dalles 133
Millbury 127
Jacksonville 120
Princeton 93
Boston 88
Munich 83
Tokyo 74
Nanjing 73
New York 73
Ottawa 63
Buffalo 62
Turku 61
São Paulo 51
Da Nang 50
Rome 49
Helsinki 48
Wilmington 42
Frankfurt am Main 41
Haiphong 41
Des Moines 38
Orem 38
Council Bluffs 35
Warsaw 35
Dallas 34
Redondo Beach 34
Seattle 33
London 31
Lawrence 30
Seoul 30
Woodbridge 29
Milan 28
Nanchang 27
Barano d'Ischia 26
Montreal 26
Brooklyn 25
Chicago 25
Dong Ket 24
Houston 24
Rio de Janeiro 24
Dearborn 23
Johannesburg 23
Stockholm 23
Mexico City 22
Atlanta 21
Chennai 21
Changsha 20
Denver 20
Formia 20
Falkenstein 19
Poplar 19
Lappeenranta 18
Nuremberg 18
Can Tho 17
Caserta 17
Hải Dương 17
Phoenix 17
Tianjin 17
Amman 16
Florence 16
Norwalk 16
Toronto 16
Biên Hòa 15
Jiaxing 15
Shenyang 15
Pune 14
Ankara 13
Guangzhou 13
Afragola 12
Belo Horizonte 12
Hebei 12
Brasília 11
Kronberg 11
Manchester 11
Nairobi 11
New Delhi 11
Ninh Bình 11
Porto Alegre 11
Washington 11
Baghdad 10
Boardman 10
Bắc Ninh 10
Salerno 10
San Francisco 10
Bangkok 9
Totale 9.310
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 391
Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors 208
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death 191
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 191
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 179
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 177
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage 172
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 169
L’aumento dell’RNAm e della proteina HIF-1α, una subunità della proteina Hypoxia Inducible Factor (HIF-1), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 167
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 167
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 167
Divergent modulation of iron regulatory proteins and ferritin biosynthesis during hypoxia/reoxygenation affect neuronal death and glial cells survival 164
NCX1 is a new rest target gene: role in cerebral ischemia 164
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 164
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 163
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 163
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 156
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 155
miR135a administration ameliorates brain ischemic damage by preventing TRPM7 activation during brain ischemia 154
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA 154
Hypoxia/reoxygenation differently modulates the activity of iron regulatory proteins and ferritin biosynthesis in rat glial cells and neurons 150
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice 149
L’aumento dell’mRNA e della proteina HIF-1a, una subunità della proteina HIF-1 (Hypoxia Inducible Factor), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 148
Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets 148
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 146
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype 144
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 143
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 142
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats 142
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 141
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 140
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 140
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 140
A new nano-encapsulated TSPO ligand reduces neuroinflammation and improves cognitive functions in Alzheimer's disease model 139
Farmacologia per le professioni sanitarie 138
Use of CMOS Image Sensor for early detection of ischemic and haemorrhagic stroke 137
Emerging Role of DREAM in Healthy Brain and Neurological Diseases 136
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 136
Divergent modulation of iron regulatory proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurones and glial cells 135
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 134
Sumoylation of sodium/calcium exchanger in brain ischemia and ischemic preconditioning 134
Neuronal death and astrocytes survival during hypoxia/reoxygenation are affected by opposite modulation of Iron Regulatory Proteins and ferritin biosynthesis 133
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 133
GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection 132
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 131
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie del sistema nervoso centrale e periferico 131
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 131
Sodium/calcium exchanger as main effector of endogenous neuroprotection elicited by ischemic tolerance 131
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 130
Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia 129
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 129
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 129
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 128
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 128
Surgical Methods to Induce Brain Preconditioning 127
Transcriptional Regulation of ncx1 Gene in the Brain 127
The NCX3 isoform of the Na(+)/Ca(2+) exchanger contributes to neuroprotection elicited by ischemic postconditioning 126
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 126
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 125
ORAI1/STIM1 INTERACTION INTERVENES IN STROKE AND IN NEUROPROTECTION INDUCED BY ISCHEMIC PRECONDITIONING THROUGH ER Ca2+ REFILLING 125
In vivo imaging of CNS microglial activation/macrophage infiltration with combined [18F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis 125
The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats. 124
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie degenerative del sistema nervoso centrale e periferico 124
Neuroprotective Role of Sodium/Calcium Exchanger, NCX1 and NCX3, in Ischemic Preconditioning 124
Ionic homeostasis in brain conditioning 124
Does Na(+)/Ca (2+) Exchanger, NCX, Represent a New Druggable Target in Stroke Intervention? 123
Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in ischemic rats 122
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 121
Farmaci Antimicotici 121
MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits 121
Stroke Causes DNA Methylation at Ncx1 Heart Promoter in the Brain Via DNMT1/MeCP2/REST Epigenetic Complex 120
HIF-1 alpha reveals a binding- activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion 120
Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT 120
Systemic administration of blood-derived exosomes induced by remote ischemic post-conditioning, by delivering a specific cluster of miRNAs, ameliorates ischemic damage and neurological function 119
Divergent modulation of Iron Regulatory Proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurons and in glial cells 119
Models and methods for conditioning the ischemic brain 119
IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE 119
NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning 118
Leptin enhances the intracellular thyroid hormone activation in skeletal muscle to boost energy balance 117
Alcohol increases spontaneous BOLD signal fluctuations in the visual network 117
Conjunctival instillation of plasminogen eliminates ocular lesion in B6.129P2-Plg(tm1Jld) transgenic mice, a model of ligneous conjunctivitis 116
Hemorrhagic Stroke Induces a Time-Dependent Upregulation of miR-150-5p and miR-181b-5p in the Bloodstream 116
Remote postconditioning ameliorates stroke damage by preventing let-7a and miR-143 up-regulation 115
Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options. 114
Modulation of ZnT-1 by Let7a unveils a therapeutic potential in amyotrophic lateral sclerosis 113
Preconditioning and Postconditioning Exert Stroke Neuroprotection Modulating NCX and ASIC1a Expression 113
miR-16-5p, miR-103-3p, and miR-27b-3p as Early Peripheral Biomarkers of Fetal Growth Restriction 113
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 112
Glutamate-independent calcium toxicity: introduction 111
nNOS and p-ERK involvement in the neuroprotection exerted by remote postconditioning in rats subjected to transient middle cerebral artery occlusion 111
Neuroprotective coordination of cell mitophagy by the F1Fo-ATPase Inhibitory Factor 1 (IF1) 111
Synthesis and Characterization of Novel Mono- and Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult 111
SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy 110
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window 110
Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke 109
Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype 109
Preconditioning in hypoxic-ischemic neonate mice triggers Na+-Ca2+ exchanger-dependent neurogenesis 108
NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning 108
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 107
The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke 107
Totale 13.670
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Categoria #
all - tutte 51.106
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.106
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202190 0 0 0 0 0 0 0 0 0 10 40 40
2021/2022882 31 5 12 30 13 32 9 34 96 65 271 284
2022/20231.120 137 119 34 94 131 126 12 72 139 180 58 18
2023/20241.077 29 115 133 82 43 76 17 351 15 28 125 63
2024/20254.433 176 216 24 58 104 259 499 290 256 412 1.731 408
2025/20268.463 964 576 1.022 909 1.596 307 1.059 468 1.004 558 0 0
Totale 17.558