IRIS
PIGNATARO, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 6.285
NA - Nord America 5.654
EU - Europa 5.211
SA - Sud America 727
AF - Africa 142
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 4
Totale 18.028
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Nazione #
US - Stati Uniti d'America 5.414
SG - Singapore 2.735
RU - Federazione Russa 2.036
IT - Italia 1.525
CN - Cina 1.229
VN - Vietnam 1.204
BR - Brasile 581
HK - Hong Kong 459
DE - Germania 357
FR - Francia 242
NL - Olanda 228
FI - Finlandia 215
GB - Regno Unito 152
CA - Canada 148
BD - Bangladesh 134
UA - Ucraina 134
IE - Irlanda 93
JP - Giappone 89
IN - India 88
SE - Svezia 69
AR - Argentina 60
MX - Messico 52
CI - Costa d'Avorio 48
KR - Corea 47
PL - Polonia 42
TR - Turchia 42
IQ - Iraq 32
ZA - Sudafrica 32
ES - Italia 27
ID - Indonesia 27
TH - Thailandia 27
EC - Ecuador 24
PH - Filippine 23
AT - Austria 22
PK - Pakistan 18
JO - Giordania 17
TW - Taiwan 15
SA - Arabia Saudita 13
KE - Kenya 12
PY - Paraguay 11
VE - Venezuela 11
CL - Cile 10
CO - Colombia 10
UZ - Uzbekistan 10
BE - Belgio 8
LT - Lituania 8
NP - Nepal 8
AZ - Azerbaigian 7
CH - Svizzera 7
IL - Israele 7
LB - Libano 7
MA - Marocco 7
TN - Tunisia 7
BG - Bulgaria 6
EG - Egitto 6
HR - Croazia 6
PE - Perù 6
BO - Bolivia 5
CZ - Repubblica Ceca 5
NG - Nigeria 5
OM - Oman 5
AE - Emirati Arabi Uniti 4
AU - Australia 4
CR - Costa Rica 4
GA - Gabon 4
HU - Ungheria 4
JM - Giamaica 4
MY - Malesia 4
SR - Suriname 4
SV - El Salvador 4
TJ - Tagikistan 4
UY - Uruguay 4
AL - Albania 3
CY - Cipro 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
ET - Etiopia 3
GR - Grecia 3
IR - Iran 3
KG - Kirghizistan 3
KH - Cambogia 3
KW - Kuwait 3
NI - Nicaragua 3
PT - Portogallo 3
ZM - Zambia 3
BH - Bahrain 2
CW - ???statistics.table.value.countryCode.CW??? 2
GD - Grenada 2
GE - Georgia 2
GP - Guadalupe 2
GT - Guatemala 2
HN - Honduras 2
KZ - Kazakistan 2
LC - Santa Lucia 2
LK - Sri Lanka 2
LV - Lettonia 2
MK - Macedonia 2
NA - Namibia 2
PR - Porto Rico 2
Totale 17.988
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Città #
Singapore 1.353
San Jose 825
Ashburn 731
Moscow 491
Chandler 485
Naples 456
Hong Kong 441
Beijing 385
Ho Chi Minh City 356
Hanoi 266
Amsterdam 191
Santa Clara 176
Los Angeles 170
Napoli 167
Hefei 166
Lauterbourg 137
The Dalles 133
Millbury 127
Jacksonville 121
Princeton 93
Boston 90
New York 89
Munich 83
Tokyo 74
Nanjing 73
Buffalo 71
Ottawa 64
Rome 62
Turku 61
Council Bluffs 57
São Paulo 52
Da Nang 50
Dallas 49
Helsinki 48
Wilmington 44
Orem 43
Frankfurt am Main 41
Haiphong 41
Des Moines 38
Warsaw 36
Redondo Beach 34
Seattle 34
London 33
Milan 33
Chicago 32
Lawrence 30
Montreal 30
Seoul 30
Woodbridge 30
Brooklyn 28
Houston 28
Nanchang 27
Barano d'Ischia 26
Atlanta 24
Dong Ket 24
Rio de Janeiro 24
Dearborn 23
Denver 23
Johannesburg 23
Mexico City 23
Stockholm 23
Phoenix 22
Chennai 21
Toronto 21
Changsha 20
Formia 20
Falkenstein 19
Poplar 19
Caserta 18
Florence 18
Lappeenranta 18
Nuremberg 18
Can Tho 17
Hải Dương 17
Tianjin 17
Amman 16
Norwalk 16
Biên Hòa 15
Jiaxing 15
Shenyang 15
Guangzhou 14
Pune 14
Ankara 13
Turin 13
Afragola 12
Belo Horizonte 12
Hebei 12
San Francisco 12
Brasília 11
Kronberg 11
Manchester 11
Nairobi 11
New Delhi 11
Ninh Bình 11
Porto Alegre 11
Washington 11
Baghdad 10
Boardman 10
Bắc Ninh 10
Charlotte 10
Totale 9.590
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 391
Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors 215
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death 197
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage 193
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 193
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 192
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 183
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 181
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 174
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 172
L’aumento dell’RNAm e della proteina HIF-1α, una subunità della proteina Hypoxia Inducible Factor (HIF-1), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 171
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 171
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 168
NCX1 is a new rest target gene: role in cerebral ischemia 167
Divergent modulation of iron regulatory proteins and ferritin biosynthesis during hypoxia/reoxygenation affect neuronal death and glial cells survival 166
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 166
Sumoylation of sodium/calcium exchanger in brain ischemia and ischemic preconditioning 160
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 159
miR135a administration ameliorates brain ischemic damage by preventing TRPM7 activation during brain ischemia 158
A new nano-encapsulated TSPO ligand reduces neuroinflammation and improves cognitive functions in Alzheimer's disease model 158
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 158
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice 156
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA 156
L’aumento dell’mRNA e della proteina HIF-1a, una subunità della proteina HIF-1 (Hypoxia Inducible Factor), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 155
Farmacologia per le professioni sanitarie 153
Hypoxia/reoxygenation differently modulates the activity of iron regulatory proteins and ferritin biosynthesis in rat glial cells and neurons 151
Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets 150
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats 150
Sodium/calcium exchanger as main effector of endogenous neuroprotection elicited by ischemic tolerance 149
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 148
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 147
Leptin enhances the intracellular thyroid hormone activation in skeletal muscle to boost energy balance 146
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 146
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype 145
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 143
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 143
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 142
Emerging Role of DREAM in Healthy Brain and Neurological Diseases 141
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 141
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 141
Use of CMOS Image Sensor for early detection of ischemic and haemorrhagic stroke 140
Neuronal death and astrocytes survival during hypoxia/reoxygenation are affected by opposite modulation of Iron Regulatory Proteins and ferritin biosynthesis 137
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 137
Divergent modulation of iron regulatory proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurones and glial cells 136
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 136
GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection 136
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie del sistema nervoso centrale e periferico 135
Surgical Methods to Induce Brain Preconditioning 135
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 135
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 134
Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in ischemic rats 133
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 133
Transcriptional Regulation of ncx1 Gene in the Brain 133
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 133
The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats. 132
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 132
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 132
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 130
Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia 129
The NCX3 isoform of the Na(+)/Ca(2+) exchanger contributes to neuroprotection elicited by ischemic postconditioning 129
Farmaci Antimicotici 129
Ionic homeostasis in brain conditioning 129
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 129
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 128
ORAI1/STIM1 INTERACTION INTERVENES IN STROKE AND IN NEUROPROTECTION INDUCED BY ISCHEMIC PRECONDITIONING THROUGH ER Ca2+ REFILLING 128
In vivo imaging of CNS microglial activation/macrophage infiltration with combined [18F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis 128
Modulation of ZnT-1 by Let7a unveils a therapeutic potential in amyotrophic lateral sclerosis 127
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 127
Neuroprotective Role of Sodium/Calcium Exchanger, NCX1 and NCX3, in Ischemic Preconditioning 127
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie degenerative del sistema nervoso centrale e periferico 126
HIF-1 alpha reveals a binding- activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion 125
Conjunctival instillation of plasminogen eliminates ocular lesion in B6.129P2-Plg(tm1Jld) transgenic mice, a model of ligneous conjunctivitis 125
Does Na(+)/Ca (2+) Exchanger, NCX, Represent a New Druggable Target in Stroke Intervention? 124
IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE 124
Stroke Causes DNA Methylation at Ncx1 Heart Promoter in the Brain Via DNMT1/MeCP2/REST Epigenetic Complex 123
Divergent modulation of Iron Regulatory Proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurons and in glial cells 123
MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits 123
K+-Dependent Na+/Ca2+ Exchanger Isoform 2, Nckx2, Takes Part in the Neuroprotection Elicited by Ischemic Preconditioning in Brain Ischemia 122
NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning 122
Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT 122
Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options. 120
Models and methods for conditioning the ischemic brain 120
Systemic administration of blood-derived exosomes induced by remote ischemic post-conditioning, by delivering a specific cluster of miRNAs, ameliorates ischemic damage and neurological function 119
Alcohol increases spontaneous BOLD signal fluctuations in the visual network 119
Hemorrhagic Stroke Induces a Time-Dependent Upregulation of miR-150-5p and miR-181b-5p in the Bloodstream 119
SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy 117
Glutamate-independent calcium toxicity: introduction 116
nNOS and p-ERK involvement in the neuroprotection exerted by remote postconditioning in rats subjected to transient middle cerebral artery occlusion 116
miR-16-5p, miR-103-3p, and miR-27b-3p as Early Peripheral Biomarkers of Fetal Growth Restriction 116
Remote postconditioning ameliorates stroke damage by preventing let-7a and miR-143 up-regulation 116
Preconditioning and Postconditioning Exert Stroke Neuroprotection Modulating NCX and ASIC1a Expression 115
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 115
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window 113
Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype 112
Neuroprotective coordination of cell mitophagy by the F1Fo-ATPase Inhibitory Factor 1 (IF1) 112
Synthesis and Characterization of Novel Mono- and Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult 112
Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke 111
NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning 111
The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke 110
Preconditioning in hypoxic-ischemic neonate mice triggers Na+-Ca2+ exchanger-dependent neurogenesis 108
Totale 14.181
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Categoria #
all - tutte 55.794
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.794
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022882 31 5 12 30 13 32 9 34 96 65 271 284
2022/20231.120 137 119 34 94 131 126 12 72 139 180 58 18
2023/20241.077 29 115 133 82 43 76 17 351 15 28 125 63
2024/20254.433 176 216 24 58 104 259 499 290 256 412 1.731 408
2025/20269.103 964 576 1.022 909 1.596 307 1.059 468 1.004 605 320 273
2026/202783 83 0 0 0 0 0 0 0 0 0 0 0
Totale 18.281