IRIS
PAGANO, BRUNO
 Distribuzione geografica
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Continente #
AS - Asia 6.682
NA - Nord America 6.128
EU - Europa 5.514
SA - Sud America 806
AF - Africa 186
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 19.324
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Nazione #
US - Stati Uniti d'America 5.901
SG - Singapore 2.970
RU - Federazione Russa 2.292
IT - Italia 1.450
CN - Cina 1.319
VN - Vietnam 1.244
BR - Brasile 652
HK - Hong Kong 448
NL - Olanda 297
DE - Germania 275
FR - Francia 263
FI - Finlandia 194
IE - Irlanda 175
GB - Regno Unito 147
CA - Canada 136
IN - India 129
JP - Giappone 121
UA - Ucraina 103
SE - Svezia 89
BD - Bangladesh 77
CI - Costa d'Avorio 72
AR - Argentina 65
MX - Messico 55
KR - Corea 48
ZA - Sudafrica 45
IQ - Iraq 37
ID - Indonesia 34
PH - Filippine 34
ES - Italia 33
PL - Polonia 31
EC - Ecuador 29
PK - Pakistan 27
TW - Taiwan 26
TH - Thailandia 24
BE - Belgio 22
TR - Turchia 22
UZ - Uzbekistan 22
CZ - Repubblica Ceca 21
OM - Oman 19
LT - Lituania 18
AT - Austria 17
GR - Grecia 15
CL - Cile 14
MA - Marocco 14
VE - Venezuela 12
PY - Paraguay 11
SI - Slovenia 10
KE - Kenya 9
MY - Malesia 9
SA - Arabia Saudita 9
EG - Egitto 8
CO - Colombia 7
DZ - Algeria 7
JO - Giordania 7
PT - Portogallo 7
AE - Emirati Arabi Uniti 6
IL - Israele 6
IR - Iran 6
LB - Libano 6
CH - Svizzera 5
GT - Guatemala 5
JM - Giamaica 5
NP - Nepal 5
PE - Perù 5
RO - Romania 5
TT - Trinidad e Tobago 5
BG - Bulgaria 4
DO - Repubblica Dominicana 4
LU - Lussemburgo 4
NO - Norvegia 4
AL - Albania 3
AU - Australia 3
AZ - Azerbaigian 3
BB - Barbados 3
ET - Etiopia 3
HU - Ungheria 3
KZ - Kazakistan 3
LY - Libia 3
MD - Moldavia 3
PS - Palestinian Territory 3
RS - Serbia 3
SR - Suriname 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BO - Bolivia 2
BY - Bielorussia 2
BZ - Belize 2
CG - Congo 2
CY - Cipro 2
DK - Danimarca 2
EE - Estonia 2
GA - Gabon 2
GY - Guiana 2
HN - Honduras 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
ME - Montenegro 2
Totale 19.271
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Città #
Singapore 1.401
San Jose 869
Chandler 676
Moscow 497
Ashburn 447
Naples 436
Hong Kong 429
Beijing 387
Ho Chi Minh City 361
Hanoi 295
Amsterdam 259
Santa Clara 225
Dallas 218
The Dalles 199
Los Angeles 173
Hefei 166
Millbury 157
Napoli 153
Lauterbourg 149
Princeton 117
Nanjing 107
Tokyo 105
Jacksonville 101
Boston 100
New York 82
Redondo Beach 73
Des Moines 72
São Paulo 69
Munich 66
Buffalo 59
Ottawa 58
Rome 58
Wilmington 53
Haiphong 52
Da Nang 49
Helsinki 49
Brooklyn 42
Houston 41
Milan 39
Denver 36
Orem 35
Lawrence 34
Dearborn 32
Frankfurt am Main 31
Nanchang 31
Salerno 31
Seattle 31
Mexico City 30
Montreal 30
Phoenix 29
Seoul 29
Chicago 28
Shenyang 28
London 26
Falkenstein 25
Atlanta 24
Warsaw 24
Turku 23
Changsha 22
Nuremberg 22
San Francisco 22
Tianjin 22
Washington 22
Jiaxing 21
Johannesburg 21
Tashkent 21
Poplar 20
Toronto 20
Woodbridge 20
Chennai 19
Council Bluffs 18
Hebei 18
Rio de Janeiro 18
Stockholm 18
Brussels 17
Redwood City 17
Florence 16
Ninh Bình 16
Biên Hòa 15
Letovice 15
Mumbai 15
Paris 15
Baghdad 14
Boardman 14
Hải Dương 14
Manchester 14
New Delhi 14
San Giorgio a Cremano 14
Belo Horizonte 13
Can Tho 13
Kronberg 13
Augusta 12
Guangzhou 12
Kochi 12
Quito 12
Thessaloniki 12
Thái Bình 12
Dublin 11
Norwalk 11
Secaucus 11
Totale 10.124
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Nome #
A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide 226
1H NMR-based metabolomics study on follicular fluid from patients with Polycystic Ovary Syndrome 220
Nuovi ligandi per G-quadruplex: un approccio chimico-fisico nella terapia anti-cancro 201
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 194
Characterisation of the dynamic interactions between complex N-glycans and human CD22 192
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 186
G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting 182
Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration 177
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes 174
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 172
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists 171
Shooting for selective drug-like DNA G-quadruplex binders 170
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 169
Common G-quadruplex binding agents found to interact with i-motif-forming DNA: Unexpected multi-target-directed compounds 168
Tetramolecular G-quadruplex Assembly: Effects of Polarity Site Inversions 163
Fluorescence enhancement in G-quadruplex folding: synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 162
Repurposing FDA-approved drugs to target G-quadruplexes in breast cancer 159
A New DNA Structural Motif: The G-Triplex 154
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures? 154
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 153
Identification of an acetal derivative of the piperonyl methyl ketone in tablets seized for suspected drug trafficking 151
Targeting of telomeric repeat-containing RNA G-quadruplexes: From screening to biophysical and biological characterization of a new hit compound 150
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 149
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 148
Unlocking the potential of protein-derived peptides to target G-quadruplex DNA: from recognition to anticancer activity 147
G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells 147
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 145
Identification of novel interactors of human telomeric G-quadruplex DNA 145
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 144
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 144
Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules 143
Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents 140
A novel dansyl-labelled TBA15 analog showing fluorescence enhancement upon G-quadruplex formation for early detection of thrombin 140
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 139
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 139
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model 139
Tailoring a lead-like compound targeting multiple G-quadruplex structures 138
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 137
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 137
Characterization of monovarietal extra virgin olive oils from the province of Béjaïa (Algeria) 137
Fluorescence enhancement in G-quadruplex folding: Synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 136
Interaction of azatrux with human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies 136
Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study 133
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 132
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 131
Combination of dl922-947 Oncolytic Adenovirus and G-Quadruplex Binders Uncovers Improved Antitumor Activity in Breast Cancer 131
Energetics of Biomolecular Interactions 130
Aptameri formanti G-quadruplex per la terapia delle malattie da prioni 130
Interaction of azatrux to human telomeric DNA: A thermodynamic analysis 130
NMR Assignment of N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide Seized as Herbal Incense for the First Time in Italy 129
Interaction of azatrux with the G-quadruplex parallel fold: biophysical insight into the binding propietes to address drug design 127
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 127
Binding of TMPyP4 to higher-order telomeric quadruplexes: a biophysical study 127
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 127
Assessing the influence of pH and cationic strength on i-motif DNA structure 127
A new fluorescent TBA for early detection of thrombin: A biophysical study 126
Synthesis and characterization of bis-triazolyl-pyridine derivatives as noncanonical DNA-interacting compounds 126
Energetic Aspects of the recognition between G-Quadruplex structures and ligands 125
Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives 124
Printed Electrochemical Strip for the Detection of miRNA-29a: A Possible Biomarker Related to Alzheimer's Disease 123
Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate 122
HMGB1 binds to the KRAS promoter G-quadruplex: A new player in oncogene transcriptional regulation? 121
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 119
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 119
A novel β-hairpin peptide derived from the ARC repressor selectively interacts with the major groove of B-DNA 119
Effects of Sequence and Base Composition on the CD and TDS Profiles of i-DNA 119
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides 118
Conformational plasticity of DNA secondary structures: probing the conversion between i-motif and hairpin species by circular dichroism and ultraviolet resonance Raman spectroscopies 118
Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition 117
Towards an analytical methodology for the screening of G-quadruplex-binding ligands 116
Stability and binding properties of a modified Thrombin binding aptamer 115
Stabilità termodinamica del multimero del telomero umano ed energetica dell’interazione con la porfirina cationica 115
An unbiased lncRNAs dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for Multiple Myeloma 114
Ligand-based drug repurposing strategy identified SARS-CoV-2 RNA G-quadruplex binders 114
Stability and binding properties of a modified Thrombin binding aptamer 114
Binding and stability of G-quadruplexes: Insights from biocalorimetry 114
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi 114
Unveiling the interaction between DNA G-quadruplexes and RG-rich peptides 113
The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies 112
Noncanonical DNA secondary structures as drug targets: The prospect of the i-motif 112
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands 112
Binding of distamycin and analogues to quadruplex structures 111
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 111
Biophysical study of the human telomeric quadruplexes-drugs interaction: a good starting point for anti cancer agents 110
Looking for new efficient G-quadruplex binders 110
New ligands for DNA telomeric G-quadruplexes: a thermodynamic approach towards anti-cancer therapy 110
Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 110
Screening of DNA G-quadruplex stabilizing ligands by nano differential scanning fluorimetry 110
Selective Binding of Distamycin A Derivative to G-Quadruolex Structure [d(TGGGGT)]4 108
Cytosine epigenetic modifications and conformational changes in G-quadruplex DNA: An ultraviolet resonance Raman spectroscopy study 107
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex 107
On the thermodynamics of folding of an i-motif DNA in solution under favorable conditions 107
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 106
Targeting G-quadruplex motifs interferes with differentiation of adipose-derived mesenchymal stem cells 105
Design, Synthesis, and Anticancer Activity of Drug-like Iron Chelators/G-Quadruplex Binders as Synergic Dual Targeting Agents 104
NMR Structure of the Complex between Distamycin A and the Four Stranded Quadruplex Structure [d(TGGGGT)]4 102
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation 102
Identifying G-quadruplex-interacting proteins in cancer-related gene promoters 101
Third International Meeting on G-quadruplex and G-assembly 101
Biophysical characterization of interaction between prion and G-quadruplex forming aptamers 101
Totale 13.443
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Categoria #
all - tutte 59.252
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.252
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202112 0 0 0 0 0 0 0 0 0 0 0 12
2021/2022880 24 3 7 9 22 25 18 43 184 63 120 362
2022/20231.633 169 121 42 197 141 186 12 165 226 237 108 29
2023/2024926 41 144 179 61 38 54 23 143 23 15 144 61
2024/20254.898 234 278 38 68 137 271 451 305 313 507 1.836 460
2025/20269.372 994 637 1.185 854 1.690 406 999 558 1.142 594 272 41
Totale 19.584