IRIS
PAGANO, BRUNO
 Distribuzione geografica
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Continente #
NA - Nord America 3.005
EU - Europa 2.065
AS - Asia 993
AF - Africa 69
SA - Sud America 11
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.147
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Nazione #
US - Stati Uniti d'America 2.943
IT - Italia 1.008
SG - Singapore 545
CN - Cina 385
NL - Olanda 258
IE - Irlanda 170
FI - Finlandia 148
DE - Germania 115
SE - Svezia 77
UA - Ucraina 69
CI - Costa d'Avorio 67
CA - Canada 61
GB - Regno Unito 56
RU - Federazione Russa 43
FR - Francia 36
IN - India 22
CZ - Repubblica Ceca 20
BE - Belgio 18
OM - Oman 15
BR - Brasile 10
ES - Italia 9
SI - Slovenia 8
KR - Corea 6
IR - Iran 4
RO - Romania 4
BG - Bulgaria 3
CH - Svizzera 3
PT - Portogallo 3
AT - Austria 2
AU - Australia 2
DK - Danimarca 2
JP - Giappone 2
PK - Pakistan 2
PL - Polonia 2
TR - Turchia 2
TW - Taiwan 2
AL - Albania 1
BS - Bahamas 1
CY - Cipro 1
EE - Estonia 1
EU - Europa 1
GR - Grecia 1
ID - Indonesia 1
IM - Isola di Man 1
IS - Islanda 1
JO - Giordania 1
LT - Lituania 1
LU - Lussemburgo 1
MA - Marocco 1
MC - Monaco 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TM - Turkmenistan 1
VN - Vietnam 1
Totale 6.147
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Città #
Chandler 676
Singapore 456
Amsterdam 245
Naples 232
Santa Clara 199
Millbury 158
Napoli 153
Ashburn 141
Princeton 118
Nanjing 105
Jacksonville 100
Beijing 89
Boston 81
Des Moines 71
Ottawa 57
Wilmington 54
Lawrence 34
Rome 34
Dearborn 32
Nanchang 31
Salerno 31
Helsinki 28
Shenyang 27
Milan 26
Houston 21
Jiaxing 21
Seattle 20
Woodbridge 20
Hebei 18
Changsha 17
Redwood City 17
Letovice 15
Boardman 14
Moscow 14
Brussels 13
Kronberg 13
Tianjin 13
Norwalk 11
Augusta 10
Torre del Greco 9
Bologna 8
Dublin 8
Kunming 8
Ljubljana 8
London 8
Paris 8
Cagliari 7
Caserta 7
Scafati 7
Ann Arbor 6
Florence 6
Los Angeles 6
Madrid 6
Quarto 6
Stockholm 6
Trieste 6
Turin 6
Verona 6
Caivano 5
Council Bluffs 5
Fairfield 5
Fucecchio 5
Mountain View 5
Padova 5
Rio Grande 5
Altamura 4
Canterbury 4
Centro 4
Changchun 4
Chuncheon 4
Como 4
Cosenza 4
Dallas 4
Falls Church 4
Fermo 4
Gurgaon 4
Orange 4
Palermo 4
Perugia 4
Pune 4
San Francisco 4
Selargius 4
Seregno 4
Solofra 4
West Lafayette 4
Bari 3
Brescia 3
Cambridge 3
Edinburgh 3
Frankfurt am Main 3
Fremont 3
Fuzhou 3
Ghent 3
Hangzhou 3
Jinan 3
Lappeenranta 3
Marigliano 3
Munich 3
New York 3
Nürnberg 3
Totale 3.707
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Nome #
Nuovi ligandi per G-quadruplex: un approccio chimico-fisico nella terapia anti-cancro 123
1H NMR-based metabolomics study on follicular fluid from patients with Polycystic Ovary Syndrome 113
Characterisation of the dynamic interactions between complex N-glycans and human CD22 100
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes 87
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 86
Common G-quadruplex binding agents found to interact with i-motif-forming DNA: Unexpected multi-target-directed compounds 75
Aptameri formanti G-quadruplex per la terapia delle malattie da prioni 73
A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide 71
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 66
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures? 66
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 65
Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules 65
Characterization of monovarietal extra virgin olive oils from the province of Béjaïa (Algeria) 63
Identification of novel interactors of human telomeric G-quadruplex DNA 62
Shooting for selective drug-like DNA G-quadruplex binders 61
Binding of distamycin and analogues to quadruplex structures 60
Fluorescence enhancement in G-quadruplex folding: synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 60
Targeting of telomeric repeat-containing RNA G-quadruplexes: From screening to biophysical and biological characterization of a new hit compound 60
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 59
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 58
Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate 58
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model 58
NMR Assignment of N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide Seized as Herbal Incense for the First Time in Italy 57
Thermodynamic analysis of quadruplex DNA-drug interaction 56
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 54
Identification of an acetal derivative of the piperonyl methyl ketone in tablets seized for suspected drug trafficking 53
Tetramolecular G-quadruplex Assembly: Effects of Polarity Site Inversions 53
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 52
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 52
A new fluorescent TBA for early detection of thrombin: A biophysical study 52
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 51
Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras 50
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 50
Binding of TMPyP4 to higher-order telomeric quadruplexes: a biophysical study 50
Tailoring a lead-like compound targeting multiple G-quadruplex structures 50
G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells 50
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 49
Energetics of quadruplex-drug recognition in anticancer therapy 47
Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones 47
Fluorescence enhancement in G-quadruplex folding: Synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 47
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 47
How are thermodynamically stable G-quadruplex-duplex hybrids? 47
Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment 47
Stability and binding properties of a modified Thrombin binding aptamer 46
Energetics of Biomolecular Interactions 46
Binding and stability of G-quadruplexes: Insights from biocalorimetry 46
A New DNA Structural Motif: The G-Triplex 46
Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study 46
Conformational plasticity of DNA secondary structures: probing the conversion between i-motif and hairpin species by circular dichroism and ultraviolet resonance Raman spectroscopies 46
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 45
Biophysical study of the human telomeric quadruplexes-drugs interaction: a good starting point for anti cancer agents 45
Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 45
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 45
Thermodynamic analysis of Quadruplex DNA-drugs interaction 44
Stabilità termodinamica del multimero del telomero umano ed energetica dell’interazione con la porfirina cationica 44
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 44
A novel dansyl-labelled TBA15 analog showing fluorescence enhancement upon G-quadruplex formation for early detection of thrombin 44
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation 44
HMGB1 binds to the KRAS promoter G-quadruplex: A new player in oncogene transcriptional regulation? 44
Effects of Sequence and Base Composition on the CD and TDS Profiles of i-DNA 44
Stability and binding properties of a modified thrombin binding aptamer 43
Interaction of azatrux with the G-quadruplex parallel fold: biophysical insight into the binding propietes to address drug design 43
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands 43
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides 43
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi 42
Analisi termodinamica dell’interazione tra ligandi e quadruple del DNA telomerico umano 41
Selective Binding of Distamycin A Derivative to G-Quadruolex Structure [d(TGGGGT)]4 41
Looking for efficient G-quadruplex ligands: Evidence for selective stabilizing properties and telomere damage by drug-like molecules 41
G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting 40
Energetic Aspects of the recognition between G-Quadruplex structures and ligands 40
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 40
Stability and binding properties of a modified Thrombin binding aptamer 39
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex 39
Structural insight into the hTERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study 38
Targeting DNA quadruplexes with distamycin A and its derivatives: An ITC and NMR study 38
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 38
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 38
A novel β-hairpin peptide derived from the ARC repressor selectively interacts with the major groove of B-DNA 38
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 38
Biophysical properties of quadruplexes formed by PNA-DNA chimeras 37
Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation 37
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 37
Assessing the influence of pH and cationic strength on i-motif DNA structure 37
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists 36
Application of "magnetic tongue" to the sensory evaluation of extra virgin olive oil 36
Interaction between prion protein and G-quadruplex-forming nucleic acids: a biophysical study 36
Biophysical characterization of interaction between prion and G-quadruplex forming aptamers 36
Noncanonical DNA secondary structures as drug targets: The prospect of the i-motif 35
Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives 35
Unveiling the interaction between DNA G-quadruplexes and RG-rich peptides 35
BioCalorimetry of G-Quadruplex Structures 34
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 33
Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes 33
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 33
Interaction of azatrux to human telomeric DNA: A thermodynamic analysis 33
New ligands for DNA telomeric G-quadruplexes: a thermodynamic approach towards anti-cancer therapy 33
Interaction of azatrux with human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies 32
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 32
Use of NMR in profiling of cocaine seizures 31
Exploring the chemical space of G-quadruplex binders: Discovery of a novel chemotype targeting the human telomeric sequence 31
Totale 4.899
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Categoria #
all - tutte 28.020
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.020
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020224 0 0 0 0 0 0 29 17 17 38 67 56
2020/2021467 27 21 33 25 52 97 47 34 50 24 45 12
2021/2022884 24 3 7 9 22 26 18 44 184 63 120 364
2022/20231.635 170 121 42 197 141 186 12 165 226 237 108 30
2023/2024930 41 144 179 61 38 54 24 143 24 15 146 61
2024/20251.052 236 284 38 68 138 274 14 0 0 0 0 0
Totale 6.381