IRIS
RODRIQUEZ, MANUELA
 Distribuzione geografica
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Continente #
EU - Europa 391
NA - Nord America 360
AS - Asia 262
AF - Africa 4
SA - Sud America 4
OC - Oceania 1
Totale 1.022
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Nazione #
US - Stati Uniti d'America 351
IT - Italia 286
SG - Singapore 157
HK - Hong Kong 49
CN - Cina 42
NL - Olanda 27
FI - Finlandia 20
DE - Germania 11
IE - Irlanda 11
SE - Svezia 10
CA - Canada 9
UA - Ucraina 7
RU - Federazione Russa 6
VN - Vietnam 6
GB - Regno Unito 5
BR - Brasile 4
CI - Costa d'Avorio 4
MV - Maldive 4
CZ - Repubblica Ceca 2
FR - Francia 2
CH - Svizzera 1
DK - Danimarca 1
ES - Italia 1
IN - India 1
IR - Iran 1
JP - Giappone 1
NZ - Nuova Zelanda 1
RO - Romania 1
TR - Turchia 1
Totale 1.022
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Città #
Singapore 135
Santa Clara 59
Hong Kong 48
Chandler 45
Rome 44
Naples 30
Ashburn 23
Napoli 19
Amsterdam 14
Millbury 14
Helsinki 12
Milan 12
Bologna 9
Ottawa 9
Dallas 8
Dearborn 8
Shenzhen 8
Turin 8
Princeton 6
Xi'an 6
Baronissi 5
Des Moines 5
Dong Ket 5
Seattle 5
Boston 4
Goiânia 4
Jacksonville 4
Lawrence 4
Malé 4
Nanjing 4
Acerra 3
Dublin 3
New York 3
Orvieto 3
Bitonto 2
Bollate 2
Buffalo 2
Casalmaiocco 2
Cerignola 2
Cesano Maderno 2
Council Bluffs 2
Espoo 2
Ferrara 2
Fisciano 2
Guangzhou 2
Görwihl 2
Hebei 2
Kronberg 2
Madrigale 2
Novara 2
Nuremberg 2
Parma 2
Pompiano 2
Portici 2
Pozzuoli 2
Salerno 2
San Giovanni al Natisone 2
San Mateo 2
Santa Maria di Sala 2
Sarno 2
Siena 2
Tianjin 2
Traversetolo 2
Trecate 2
Varedo 2
Venice 2
Abidjan 1
Agrate Conturbia 1
Auckland 1
Barcelona 1
Boardman 1
Brno 1
Cesa 1
Changchun 1
Changsha 1
Chicago 1
Chieti 1
Chongqing 1
College Station 1
Fermo 1
Ferrara di Monte Baldo 1
Hangzhou 1
Hefei 1
Jiaxing 1
Jinan 1
Leawood 1
Los Angeles 1
Mercato San Severino 1
Middlesbrough 1
Nanchang 1
Pasadena 1
Prague 1
Praia a Mare 1
Pune 1
Sinalunga 1
Springfield 1
Trieste 1
Wilmington 1
Wuxi 1
Zurich 1
Totale 671
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Nome #
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 160
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 71
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 64
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 64
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 61
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 46
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 41
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 33
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 31
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 29
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 28
Total synthesis and biological evaluation of halipeptins A and D and analogues. 25
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 24
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 22
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 20
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 20
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 17
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 17
Co‐Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest 16
Towards an improvement of anticancer activity of benzyl adenosine analogs 16
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications 14
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 13
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 13
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 13
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues 13
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: Role of Annexin A1 12
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 12
Is it time to integrate sex and gender into drug design and development? 11
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 11
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 11
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 9
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 9
Synthesis and biological evaluation of Santacruzamate-A based analogues 9
Synthesis of enantiopure 7-substituted azepane-2-carboxylic acids as templates for conformationally constrained peptidomimetics 9
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 9
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid 9
Synthesis and biological evaluation of small Molecules derivatives of the natural Histone deacetylase inhibitor FR235222 8
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis 8
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 8
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells 7
Chemistry and biology of chromatin remodeling agents: State of art and future perspectives of HDAC inhibitors 7
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 6
Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core 6
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 6
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 6
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1 5
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine 5
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure 5
Colorimetric tools for solid-phase organic synthesis 5
Histone deacetylase inhibitors in the treatment of hematological malignancies 5
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 5
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222 5
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines 5
Steroidal hydroxamic acid derivatives: A structurally novel class of HDAC inhibitors 5
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222 4
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 4
Developing Molecular Diversity in the Construction of a Family of Bicyclic Isoxazolines Scaffolds: Control of Regio-and Diastereoselectivities 4
Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors 3
Microwaves enhance cyclisation of tetrapeptides 3
Targeting STAT3 in cancer inhibition 3
Structural features of peptides derived from feline immunodeficiency virus TM-Glycoprotein 3
?-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 2
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 2
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide 1
Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action 1
Totale 1.119
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Categoria #
all - tutte 5.655
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.655
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202013 0 0 0 0 0 0 2 1 1 0 2 7
2020/202153 1 1 5 1 1 8 4 5 14 1 7 5
2021/202262 2 0 0 2 2 1 3 4 9 5 8 26
2022/2023149 10 10 1 11 18 25 12 11 16 17 9 9
2023/2024252 7 16 36 16 15 11 15 14 14 6 30 72
2024/2025521 131 141 31 43 35 69 71 0 0 0 0 0
Totale 1.119