IRIS
RODRIQUEZ, MANUELA
 Distribuzione geografica
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Continente #
AS - Asia 2.727
EU - Europa 1.494
NA - Nord America 1.366
SA - Sud America 287
AF - Africa 42
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.925
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Nazione #
US - Stati Uniti d'America 1.301
SG - Singapore 1.154
CN - Cina 709
RU - Federazione Russa 613
IT - Italia 506
VN - Vietnam 301
HK - Hong Kong 217
BR - Brasile 213
BD - Bangladesh 89
FR - Francia 83
KR - Corea 75
NL - Olanda 71
JP - Giappone 66
DE - Germania 52
GB - Regno Unito 38
FI - Finlandia 37
CA - Canada 31
IN - India 30
MX - Messico 23
AR - Argentina 22
EC - Ecuador 18
SE - Svezia 17
ZA - Sudafrica 17
UA - Ucraina 15
IE - Irlanda 13
ES - Italia 12
IQ - Iraq 11
PH - Filippine 10
PL - Polonia 10
TH - Thailandia 10
ID - Indonesia 8
TR - Turchia 8
CO - Colombia 7
EG - Egitto 7
VE - Venezuela 7
CL - Cile 6
AT - Austria 5
PK - Pakistan 5
TW - Taiwan 5
AL - Albania 4
CH - Svizzera 4
CI - Costa d'Avorio 4
MV - Maldive 4
NZ - Nuova Zelanda 4
PE - Perù 4
PY - Paraguay 4
UY - Uruguay 4
UZ - Uzbekistan 4
AE - Emirati Arabi Uniti 3
BE - Belgio 3
MA - Marocco 3
SA - Arabia Saudita 3
TN - Tunisia 3
AU - Australia 2
AZ - Azerbaigian 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GR - Grecia 2
HN - Honduras 2
IL - Israele 2
IR - Iran 2
JM - Giamaica 2
KZ - Kazakistan 2
MY - Malesia 2
RO - Romania 2
BB - Barbados 1
BF - Burkina Faso 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BZ - Belize 1
CR - Costa Rica 1
CW - ???statistics.table.value.countryCode.CW??? 1
DK - Danimarca 1
DZ - Algeria 1
JO - Giordania 1
KE - Kenya 1
KH - Cambogia 1
KW - Kuwait 1
MT - Malta 1
NC - Nuova Caledonia 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PT - Portogallo 1
RW - Ruanda 1
SO - Somalia 1
TT - Trinidad e Tobago 1
UG - Uganda 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.925
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Città #
Singapore 601
Hefei 366
San Jose 255
Hong Kong 201
Ashburn 148
Moscow 147
Beijing 121
Ho Chi Minh City 85
Santa Clara 74
Naples 71
Hanoi 69
Seoul 67
Los Angeles 63
Rome 60
Tokyo 60
The Dalles 55
Lauterbourg 52
Dallas 47
Chandler 45
New York 34
Milan 30
Amsterdam 24
São Paulo 23
Buffalo 22
Redondo Beach 20
Napoli 19
Helsinki 17
Chicago 16
Council Bluffs 14
Millbury 14
Bologna 13
Boston 13
Da Nang 13
Orem 13
Turin 12
Brooklyn 11
Shenzhen 11
Atlanta 10
Falkenstein 10
Johannesburg 10
Munich 10
Ottawa 10
Haiphong 9
Mexico City 9
Chennai 8
Dearborn 8
Denver 8
Rio de Janeiro 8
Seattle 8
Frankfurt am Main 7
Phoenix 7
Xi'an 7
Fisciano 6
Manchester 6
Ninh Bình 6
Nuremberg 6
Poplar 6
Princeton 6
Quito 6
Thái Bình 6
Toronto 6
Turku 6
Warsaw 6
Baronissi 5
Biên Hòa 5
Can Tho 5
Des Moines 5
Dong Ket 5
Goiânia 5
Houston 5
Jacksonville 5
Lappeenranta 5
London 5
Porto Alegre 5
Stockholm 5
Bangkok 4
Belo Horizonte 4
Cairo 4
Dublin 4
Guayaquil 4
Hải Dương 4
Jinan 4
Kochi 4
Lawrence 4
Malé 4
Montevideo 4
Montreal 4
Nanjing 4
Orta di Atella 4
Rochdale 4
Tashkent 4
Zurich 4
Abu Dhabi 3
Acerra 3
Ankara 3
Asunción 3
Auckland 3
Baghdad 3
Brasília 3
Buenos Aires 3
Totale 3.253
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Nome #
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 327
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 219
Co‐Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest 153
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 152
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 148
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 147
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 141
Total synthesis and biological evaluation of halipeptins A and D and analogues. 140
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide 128
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 124
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 120
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 119
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 119
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 119
Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action 117
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications 116
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 115
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 112
Is it time to integrate sex and gender into drug design and development? 112
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 111
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 111
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 109
Endoplasmic Reticulum Stress and Its Role in Metabolic Reprogramming of Cancer 106
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 99
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 99
Towards an improvement of anticancer activity of benzyl adenosine analogs 96
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues 93
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 90
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 87
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 86
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 85
Synthesis of enantiopure 7-substituted azepane-2-carboxylic acids as templates for conformationally constrained peptidomimetics 84
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 82
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis 81
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 78
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 76
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222 75
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: Role of Annexin A1 72
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 70
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine 70
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 70
Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core 68
Synthesis and biological evaluation of small Molecules derivatives of the natural Histone deacetylase inhibitor FR235222 68
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid 68
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 67
Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors 66
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 66
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells 62
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 61
Colorimetric tools for solid-phase organic synthesis 60
Chemistry and biology of chromatin remodeling agents: State of art and future perspectives of HDAC inhibitors 60
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure 59
Developing Molecular Diversity in the Construction of a Family of Bicyclic Isoxazolines Scaffolds: Control of Regio-and Diastereoselectivities 58
Histone deacetylase inhibitors in the treatment of hematological malignancies 57
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1 54
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222 54
Microwaves enhance cyclisation of tetrapeptides 52
Targeting STAT3 in cancer inhibition 48
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 43
?-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 42
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines 42
Steroidal hydroxamic acid derivatives: A structurally novel class of HDAC inhibitors 39
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 37
Structural features of peptides derived from feline immunodeficiency virus TM-Glycoprotein 35
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 34
Synthesis and biological evaluation of Santacruzamate-A based analogues 31
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 27
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 14
Totale 6.030
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Categoria #
all - tutte 17.645
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.645
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202262 2 0 0 2 2 1 3 4 9 5 8 26
2022/2023149 10 10 1 11 18 25 12 11 16 17 9 9
2023/2024252 7 16 36 16 15 11 15 14 14 6 30 72
2024/20251.821 131 141 31 43 35 69 212 158 77 171 575 178
2025/20263.545 386 513 471 426 494 125 211 207 287 179 106 140
2026/202766 66 0 0 0 0 0 0 0 0 0 0 0
Totale 6.030