2-Methyl-1,4-benzodiazepin-5-ones were synthesized from isatoic anhydrides via cyclization of N-allyl-2-aminobenzamides with application of microwave irradn. Conventional heating and microwave irradn. of the reactions were compared. Synthesis by microwave irradn. gave the desired compds. in better yields than by conventional heating. Overall times for the syntheses were considerably reduced.
Microwave enhanced solution synthesis of 1,4-benzodiazepin-5-ones / Santagada, Vincenzo; Perissutti, Elisa; Fiorino, Ferdinando; Vivenzio, B; Caliendo, Giuseppe. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 42:12(2001), pp. 2397-2400.
Microwave enhanced solution synthesis of 1,4-benzodiazepin-5-ones.
SANTAGADA, VINCENZO;PERISSUTTI, ELISA;FIORINO, FERDINANDO;CALIENDO, GIUSEPPE
2001
Abstract
2-Methyl-1,4-benzodiazepin-5-ones were synthesized from isatoic anhydrides via cyclization of N-allyl-2-aminobenzamides with application of microwave irradn. Conventional heating and microwave irradn. of the reactions were compared. Synthesis by microwave irradn. gave the desired compds. in better yields than by conventional heating. Overall times for the syntheses were considerably reduced.File in questo prodotto:
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